|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||64987 Da|
|Positive Control||WB: VEC, 293 and A549 cell lysates|
|Application & Usage||WB 1:500-1:2000; E 1:20000|
|Other Names||M-phase inducer phosphatase 2, Dual specificity phosphatase Cdc25B, CDC25B, CDC25HU2|
|Handling||The antibody solution should be gently mixed before use|
|Reconstitution & Storage||-20°C|
|Precautions||Phospho-Cdc25B (Ser323) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, spindle pole|
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