|Host||Purified From Concentrated Hybridoma Tissue Culture Supernatant.|
|Endotoxin||<0.01EU/ µg purified protein (LAL test; Lonza).|
|Application Note||FC,Functional Application, Depletion of B cells in vivo,|
|Calculated MW||18798 Da|
|Other Names||BAFF Receptor; BR3; BlySR3; CD268; TNFRSF13C|
|Target/Specificity||Recognizes mouse BAFF-R.|
|Format||Liquid. In PBS containing 0.02% sodium azide.|
|Reconstitution & Storage||Stable for at least 1 year after receipt when stored at -20°C.|
|Precautions||Functional BAFF-R (mouse) Antibody, mAb is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||Baffr, Bcmd, Br3|
|Function||B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.|
|Cellular Location||Membrane; Single-pass type III membrane protein|
|Tissue Location||Highly expressed in spleen and testis; detected at lower levels in lung and thymus|
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Provided below are standard protocols that you may find useful for product applications.
Three receptors for BAFF were recently identified and designated TACI, BCMA and BAFF-R. BAFF-R signaling is essential for B cell development, survival and humoral immune responses.
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