|Application ||WB, E|
|Other Accession||NP_061178.1, 55527|
|Calculated MW||73639 Da|
|Other Names||Protein fem-1 homolog A, FEM1a, FEM1-alpha, Prostaglandin E receptor 4-associated protein, FEM1A, EPRAP|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FEM1A / APRAP Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable component of an E3 ubiquitin-protein ligase complex, in which it may act as a substrate recognition subunit (By similarity). May participate in antiinflammatory signaling via its interaction with PTGER4.|
|Tissue Location||Present in macrophages derived from peripheral blood monocytes. Also present in atheromata (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
Prostaglandin E receptor type 4-associated protein interacts directly
with NF-kappaB1 and attenuates macrophage activation. Minami M, Shimizu K, Okamoto Y, Folco E, Ilasaca ML, Feinberg MW, Aikawa M, Libby P. J Biol Chem. 2008 Apr 11;283(15):9692-703. PMID: 18270204
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