|Application ||WB, E|
|Other Accession||NP_001015049.1, NP_004864.1, NP_001015048.1, 9529|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||51200 Da|
|Other Names||BAG family molecular chaperone regulator 5, BAG-5, Bcl-2-associated athanogene 5, BAG5, KIAA0873|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BAG5 (N Terminus) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits both auto-ubiquitination of PRKN and ubiquitination of target proteins by PRKN (By similarity). May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding.|
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Provided below are standard protocols that you may find useful for product applications.
Variants (NP_004864.1; NP_001015048.1) encode the same isoform.
An evolutionarily conserved family of Hsp70/Hsc70 molecular chaperone regulators. Takayama S, Xie Z, Reed JC. J Biol Chem. 1999 Jan 8;274(2):781-6. PMID: 9873016
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