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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   KF1 / ZFP103 Antibody (C-Term)   

KF1 / ZFP103 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00237
Other Accession NP_005658.1, 7844
Predicted Human, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Additional Information
Other Names E3 ubiquitin-protein ligase RNF103, 6.3.2.-, KF-1, hKF-1, RING finger protein 103, Zinc finger protein 103 homolog, Zfp-103, RNF103, ZFP103
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKF1 / ZFP103 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RNF103
Synonyms ZFP103
Function Acts as an E2-dependent E3 ubiquitin-protein ligase, probably involved in the ER-associated protein degradation pathway.
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Highly expressed in the normal cerebellum but not in the cerebral cortex. EMBL; D76444; BAA19739.1; -; mRNA EMBL; AB052743; BAB20900.1; -; Genomic_DNA EMBL; AK314180; BAG36861.1; -; mRNA EMBL; AC015971; AAX93079.1; -; Genomic_DNA EMBL; BC035053; AAH35053.1; -; mRNA EMBL; BC110333; AAI10334.1; -; mRNA CCDS; CCDS33237.1; - PIR; JC5392; JC5392 RefSeq; NP_001185880.1; NM_001198951.1 RefSeq; NP_001185881.1; NM_001198952.1 RefSeq; NP_005658.1; NM_005667.3 UniGene; Hs.469199; - UniGene; Hs.731426; - ProteinModelPortal; O00237; - SMR; O00237; - BioGrid; 113601; 13 IntAct; O00237; 9 STRING; 9606.ENSP00000237455; - iPTMnet; O00237; - PhosphoSitePlus; O00237; - BioMuta; RNF103; - PaxDb; O00237; - PeptideAtlas; O00237; - PRIDE; O00237; - ProteomicsDB; 47801; - DNASU; 7844; - Ensembl; ENST00000237455; ENSP00000237455; ENSG00000239305 GeneID; 7844; - KEGG; hsa:7844; - UCSC; uc002srn.4; human CTD; 7844; - DisGeNET; 7844; - EuPathDB; HostDB:ENSG00000239305.6; - GeneCards; RNF103; - HGNC; HGNC:12859; RNF103 HPA; HPA057922; - MIM; 602507; gene neXtProt; NX_O00237; - OpenTargets; ENSG00000239305; - PharmGKB; PA37448; - eggNOG; KOG0800; Eukaryota eggNOG; ENOG41121N2; LUCA GeneTree; ENSGT00390000006413; - HOGENOM; HOG000006578; - HOVERGEN; HBG054144; - InParanoid; O00237; - KO; K15695; - OMA; GKVHWEK; - OrthoDB; 1487241at2759; - PhylomeDB; O00237; - TreeFam; TF329229; - Reactome; R-HSA-901032; ER Quality Control Compartment (ERQC) UniPathway; UPA00143; - GenomeRNAi; 7844; - PRO; PR:O00237; - Proteomes; UP000005640; Chromosome 2 Bgee; ENSG00000239305; Expressed in 234 organ(s), highest expression level in middle temporal gyrus Genevisible; O00237; HS GO; GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB GO; GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome GO; GO:0044322; C:endoplasmic reticulum quality control compartment; IEA:GOC GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW GO; GO:0061630; F:ubiquitin protein ligase activity; TAS:Reactome GO; GO:0004842; F:ubiquitin-protein transferase activity; IDA:UniProtKB GO; GO:0007417; P:central nervous system development; TAS:ProtInc GO; GO:1904380; P:endoplasmic reticulum mannose trimming; TAS:Reactome GO; GO:0016567; P:protein ubiquitination; IDA:UniProtKB GO; GO:0030433; P:ubiquitin-dependent ERAD pathway; IDA:UniProtKB Gene3D;; -; 1 InterPro; IPR001841; Znf_RING InterPro; IPR013083; Znf_RING/FYVE/PHD Pfam; PF13639; zf-RING_2; 1 SMART; SM00184; RING; 1 PROSITE; PS50089; ZF_RING_2; 1 1: Evidence at protein level; Complete proteome; Endoplasmic reticulum; Membrane; Metal-binding; Reference proteome; Transferase; Transmembrane; Transmembrane helix; Ubl conjugation pathway; Zinc; Zinc-finger CHAIN 1 685 E3 ubiquitin-protein ligase RNF103 /FTId=PRO_0000056084 TRANSMEM 6 26 Helical. TRANSMEM 326 346 Helical. TRANSMEM 366 386 Helical. TRANSMEM 411 431 Helical. ZN_FING 621 663 RING-type. {ECO:0000255|PROSITE- ProRule:PRU00175} MUTAGEN 621 621 C->S: Loss of E2-dependent ubiquitination CONFLICT 22 22 F -> L (in Ref. 3; BAG36861) CONFLICT 251 251 S -> P (in Ref. 5; AAH35053) CONFLICT 287 287 S -> P (in Ref. 3; BAG36861) CONFLICT 502 502 P -> H (in Ref. 5; AAH35053) SEQUENCE 685 AA; 79405 MW; 5AE7283EB38F533F CRC64; MWLKLFFLLL YFLVLFVLAR FFEAIVWYET GIFATQLVDP VALSFKKLKT ILECRGLGYS GLPEKKDVRE LVEKSGDLME GELYSALKEE EASESVSSTN FSGEMHFYEL VEDTKDGIWL VQVIANDRSP LVGKIHWEKM VKKVSRFGIR TGTFNCSSDP RYCRRRGWVR STLIMSVPQT STSKGKVMLK EYSGRKIEVE HIFKWITAHA ASRIKTIYNA EHLKEEWNKS DQYWLKIYLF ANLDQPPAFF SALSIKFTGR VEFIFVNVEN WDNKSYMTDI GIYNMPSYIL RTPEGIYRYG NHTGEFISLQ AMDSFLRSLQ PEVNDLFVLS LVLVNLMAWM DLFITQGATI KRFVVLISTL GTYNSLLIIS WLPVLGFLQL PYLDSFYEYS LKLLRYSNTT TLASWVRADW MFYSSHPALF LSTYLGHGLL IDYFEKKRRR NNNNDEVNAN NLEWLSSLWD WYTSYLFHPI ASFQNFPVES DWDEDPDLFL ERLAFPDLWL HPLIPTDYIK NLPMWRFKCL GVQSEEEMSE GSQDTENDSE SENTDTLSSE KEVFEDKQSV LHNSPGTASH CDAEACSCAN KYCQTSPCER KGRSYGSYNT NEDMEPDWLT WPADMLHCTE CVVCLENFEN GCLLMGLPCG HVFHQNCIVM WLAGGRHCCP VCRWPSYKKK QPYAQHQPLS NDVPS
Research Areas
Citations (0)

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Cloning of human and mouse cDNAs encoding novel zinc finger proteins expressed in cerebellum and hippocampus. Yasojima K, Tsujimura A, Mizuno T, Shigeyoshi Y, Inazawa J, Kikuno R, Kuma K, Ohkubo K, Hosokawa Y, Ibata Y, Abe T, Miyata T, Matsubara K, Nakajima K, Hashimoto-Gotoh T. Biochem Biophys Res Commun. 1997 Feb 13;231(2):481-7. PMID: 9070305

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$ 358.00
Cat# AF2337a
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