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FOXD2 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60548
Other Accession NP_004465.3, 2306, 17301 (mouse)
Predicted Human, Mouse, Rat
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Additional Information
Other Names Forkhead box protein D2, Forkhead-related protein FKHL17, Forkhead-related transcription factor 9, FREAC-9, FOXD2, FKHL17, FREAC9
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOXD2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXD2
Synonyms FKHL17, FREAC9
Function Probable transcription factor involved in embryogenesis and somatogenesis.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00089}
Tissue Location Kidney specific.. EMBL; AF042832; AAC15421.1; -; mRNA EMBL; AL607122; -; NOT_ANNOTATED_CDS; Genomic_DNA CCDS; CCDS30708.1; - RefSeq; NP_004465.3; NM_004474.3 UniGene; Hs.166188; - ProteinModelPortal; O60548; - SMR; O60548; - BioGrid; 108595; 3 IntAct; O60548; 19 iPTMnet; O60548; - PhosphoSitePlus; O60548; - BioMuta; FOXD2; - EPD; O60548; - jPOST; O60548; - PaxDb; O60548; - PeptideAtlas; O60548; - PRIDE; O60548; - ProteomicsDB; 49466; - Ensembl; ENST00000334793; ENSP00000335493; ENSG00000186564 GeneID; 2306; - KEGG; hsa:2306; - UCSC; uc001crm.3; human CTD; 2306; - DisGeNET; 2306; - EuPathDB; HostDB:ENSG00000186564.5; - GeneCards; FOXD2; - HGNC; HGNC:3803; FOXD2 MIM; 602211; gene neXtProt; NX_O60548; - OpenTargets; ENSG00000186564; - PharmGKB; PA28220; - eggNOG; KOG2294; Eukaryota eggNOG; COG5025; LUCA GeneTree; ENSGT00940000157140; - HOGENOM; HOG000231285; - InParanoid; O60548; - KO; K09397; - OMA; CEIMSSE; - OrthoDB; 1270467at2759; - PhylomeDB; O60548; - TreeFam; TF316127; - GenomeRNAi; 2306; - PRO; PR:O60548; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000186564; Expressed in 74 organ(s), highest expression level in mucosa of transverse colon Genevisible; O60548; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0001228; F:DNA-binding transcription activator activity, RNA polymerase II-specific; IC:NTNU_SB GO; GO:0003700; F:DNA-binding transcription factor activity; TAS:ProtInc GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; ISA:NTNU_SB GO; GO:0043565; F:sequence-specific DNA binding; IDA:NTNU_SB GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central GO; GO:0030154; P:cell differentiation; IBA:GO_Central GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IDA:NTNU_SB GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central CDD; cd00059; FH; 1 Gene3D;; -; 1 InterPro; IPR001766; Fork_head_dom InterPro; IPR018122; TF_fork_head_CS_1 InterPro; IPR030456; TF_fork_head_CS_2 InterPro; IPR036388; WH-like_DNA-bd_sf InterPro; IPR036390; WH_DNA-bd_sf Pfam; PF00250; Forkhead; 1 PRINTS; PR00053; FORKHEAD SMART; SM00339; FH; 1 SUPFAM; SSF46785; SSF46785; 1 PROSITE; PS00657; FORK_HEAD_1; 1 PROSITE; PS00658; FORK_HEAD_2; 1 PROSITE; PS50039; FORK_HEAD_3; 1 1: Evidence at protein level; Complete proteome; DNA-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Transcription; Transcription regulation CHAIN 1 495 Forkhead box protein D2 /FTId=PRO_0000091815 DNA_BIND 126 217 Fork-head. {ECO:0000255|PROSITE- ProRule:PRU00089} COMPBIAS 227 353 Pro-rich COMPBIAS 247 464 Ala-rich COMPBIAS 342 447 Gly-rich MOD_RES 96 96 Phosphoserine VARIANT 368 368 A -> P (in dbSNP:rs2405913) /FTId=VAR_061185 CONFLICT 293 293 H -> HPH (in Ref. 1; AAC15421) SEQUENCE 495 AA; 48748 MW; E905950E1FA94565 CRC64; MTLGSCCCEI MSSESSPAAL SEADADIDVV GGGSGGGELP ARSGPRAPRD VLPHGHEPPA EEAEADLAED EEESGGCSDG EPRALASRGA AAAAGSPGPG AAAARGAAGP GPGPPSGGAA TRSPLVKPPY SYIALITMAI LQSPKKRLTL SEICEFISGR FPYYREKFPA WQNSIRHNLS LNDCFVKIPR EPGNPGKGNY WTLDPESADM FDNGSFLRRR KRFKRQPLPP PHPHPHPHPE LLLRGGAAAA GDPGAFLPGF AAYGAYGYGY GLALPAYGAP PPGPAPHPHP HPHAFAFAAA AAAAPCQLSV PPGRAAAPPP GPPTASVFAG AGSAPAPAPA SGSGPGPGPA GLPAFLGAEL GCAKAFYAAS LSPPAAGTAA GLPTALLRQG LKTDAGGGAG GGGAGAGQRP SFSIDHIMGH GGGGAAPPGA GEGSPGPPFA AAAGPGGQAQ VLAMLTAPAL APVAGHIRLS HPGDALLSSG SRFASKVAGL SGCHF
Research Areas
Citations (0)

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A winged helix forkhead (FOXD2) tunes sensitivity to cAMP in T lymphocytes through regulation of cAMP-dependent protein kinase RIalpha. Johansson CC, Dahle MK, Blomqvist SR, Gronning LM, Aandahl EM, Enerback S, Tasken K. J Biol Chem. 2003 May 9;278(19):17573-9. Epub 2003 Mar 05. PMID: 12621056

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$ 358.00
Cat# AF2347a
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