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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   FOXL1 / FKH6 / FREAC7 Antibody (C-Term)   

FOXL1 / FKH6 / FREAC7 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q12952
Other Accession NP_005241.1, 2300
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Additional Information
Other Names Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7, FOXL1, FKHL11, FREAC7
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFOXL1 / FKH6 / FREAC7 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXL1
Synonyms FKHL11, FREAC7
Function Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity).
Cellular Location Nucleus. EMBL; AF315075; AAG40312.1; -; Genomic_DNA EMBL; AC009108; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC117226; AAI17227.1; -; mRNA EMBL; U13225; AAA92042.1; -; Genomic_DNA CCDS; CCDS10959.1; - PIR; S51630; S51630 RefSeq; NP_005241.1; NM_005250.2 UniGene; Hs.533830; - ProteinModelPortal; Q12952; - SMR; Q12952; - BioGrid; 108589; 125 IntAct; Q12952; 117 MINT; Q12952; - STRING; 9606.ENSP00000326272; - iPTMnet; Q12952; - PhosphoSitePlus; Q12952; - BioMuta; FOXL1; - DMDM; 13638268; - EPD; Q12952; - jPOST; Q12952; - PaxDb; Q12952; - PeptideAtlas; Q12952; - PRIDE; Q12952; - ProteomicsDB; 59047; - Ensembl; ENST00000320241; ENSP00000326272; ENSG00000176678 GeneID; 2300; - KEGG; hsa:2300; - UCSC; uc002fjr.4; human CTD; 2300; - DisGeNET; 2300; - EuPathDB; HostDB:ENSG00000176678.5; - GeneCards; FOXL1; - HGNC; HGNC:3817; FOXL1 MIM; 603252; gene neXtProt; NX_Q12952; - OpenTargets; ENSG00000176678; - PharmGKB; PA28234; - eggNOG; KOG2294; Eukaryota eggNOG; COG5025; LUCA GeneTree; ENSGT00940000162251; - HOGENOM; HOG000112632; - HOVERGEN; HBG051650; - InParanoid; Q12952; - KO; K09405; - OMA; PFNASLM; - OrthoDB; 1270467at2759; - PhylomeDB; Q12952; - TreeFam; TF316127; - SignaLink; Q12952; - GenomeRNAi; 2300; - PRO; PR:Q12952; - Proteomes; UP000005640; Chromosome 16 Bgee; ENSG00000176678; Expressed in 102 organ(s), highest expression level in left coronary artery ExpressionAtlas; Q12952; baseline and differential Genevisible; Q12952; HS GO; GO:0005634; C:nucleus; IBA:GO_Central GO; GO:0003677; F:DNA binding; IDA:MGI GO; GO:0008301; F:DNA binding, bending; NAS:UniProtKB GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:UniProtKB GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; ISA:NTNU_SB GO; GO:0043565; F:sequence-specific DNA binding; IDA:UniProtKB GO; GO:0009653; P:anatomical structure morphogenesis; IBA:GO_Central GO; GO:0030154; P:cell differentiation; IBA:GO_Central GO; GO:0007507; P:heart development; IMP:DFLAT GO; GO:0007275; P:multicellular organism development; NAS:UniProtKB GO; GO:0061146; P:Peyer's patch morphogenesis; IEA:Ensembl GO; GO:0030166; P:proteoglycan biosynthetic process; ISS:UniProtKB GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central GO; GO:0030111; P:regulation of Wnt signaling pathway; ISS:UniProtKB GO; GO:0007495; P:visceral mesoderm-endoderm interaction involved in midgut development; ISS:UniProtKB CDD; cd00059; FH; 1 Gene3D;; -; 1 InterPro; IPR001766; Fork_head_dom InterPro; IPR018122; TF_fork_head_CS_1 InterPro; IPR030456; TF_fork_head_CS_2 InterPro; IPR036388; WH-like_DNA-bd_sf InterPro; IPR036390; WH_DNA-bd_sf Pfam; PF00250; Forkhead; 1 PRINTS; PR00053; FORKHEAD SMART; SM00339; FH; 1 SUPFAM; SSF46785; SSF46785; 1 PROSITE; PS00657; FORK_HEAD_1; 1 PROSITE; PS00658; FORK_HEAD_2; 1 PROSITE; PS50039; FORK_HEAD_3; 1 2: Evidence at transcript level; Complete proteome; DNA-binding; Nucleus; Reference proteome; Transcription; Transcription regulation CHAIN 1 345 Forkhead box protein L1 /FTId=PRO_0000091859 DNA_BIND 48 139 Fork-head. {ECO:0000255|PROSITE- ProRule:PRU00089} SEQUENCE 345 AA; 36490 MW; 015D86B57DF3BBC6 CRC64; MSHLFDPRLP ALAASPMLYL YGPERPGLPL AFAPAAALAA SGRAETPQKP PYSYIALIAM AIQDAPEQRV TLNGIYQFIM DRFPFYHDNR QGWQNSIRHN LSLNDCFVKV PREKGRPGKG SYWTLDPRCL DMFENGNYRR RKRKPKPGPG APEAKRPRAE THQRSAEAQP EAGSGAGGSG PAISRLQAAP AGPSPLLDGP SPPAPLHWPG TASPNEDAGD AAQGAAAVAV GQAARTGDGP GSPLRPASRS SPKSSDKSKS FSIDSILAGK QGQKPPSGDE LLGGAKPGPG GRLGASLLAA SSSLRPPFNA SLMLDPHVQG GFYQLGIPFL SYFPLQVPDT VLHFQ
Research Areas
Citations (0)

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Mesenchymal transcription factor Fkh6 is essential for the development and differentiation of parietal cells. Fukamachi H, Fukuda K, Suzuki M, Furumoto T, Ichinose M, Shimizu S, Tsuchiya S, Horie S, Suzuki Y, Saito Y, Watanabe K, Taniguchi M, Koseki H. Biochem Biophys Res Commun. 2001 Feb 2;280(4):1069-76. PMID: 11162636

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$ 358.00
Cat# AF2349a
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