|Application ||WB, E|
|Other Accession||NP_002066.1, 2784|
|Predicted||Mouse, Rat, Dog, Cow|
|Calculated MW||37221 Da|
|Other Names||Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3, Transducin beta chain 3, GNB3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNB3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction.|
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Provided below are standard protocols that you may find useful for product applications.
No cross-reactivity expected with GNB1, 2 and 4
Hypertension, obesity and gnb3 gene variants. Danoviz ME, Pereira AC, Mill JG, Krieger JE. Clin Exp Pharmacol Physiol. 2006 Mar;33(3):248-52. PMID: 16487269
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