|Other Accession||NP_000785.1, 1812, 13488 (mouse), 24316 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||49293 Da|
|Other Names||D(1A) dopamine receptor, Dopamine D1 receptor, DRD1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Dopamine receptor D1 / DRD1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14.|
|Tissue Location||Detected in caudate, nucleus accumbens and in the olfactory tubercle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens. Lee KW, Kim Y, Kim AM, Helmin K, Nairn AC, Greengard P. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3399-404. Epub 2006 Feb 21. PMID: 16492766
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.