|Application ||WB, IHC, E|
|Other Accession||NP_037458.3, 29919, 76482 (mouse), 291784 (rat)|
|Predicted||Mouse, Rat, Dog|
|Calculated MW||74975 Da|
|Other Names||Uncharacterized protein C18orf8, Colon cancer-associated protein Mic1, Mic-1, C18orf8, MIC1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MIC1 / C18orf8 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Componement of the CCZ1-MON1 RAB7A guanine exchange factor (GEF). Acts as a positive regulator of CCZ1-MON1A/B function necessary for endosomal/autophagic flux and efficient RAB7A localization (PubMed:29038162).|
|Cellular Location||Lysosome membrane. Late endosome membrane|
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Global, in vivo, and site-specific phosphorylation dynamics in signaling
networks. Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M Cell. 2006 Nov 3;127(3):635-48. PMID: 17081983
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