|Other Accession||NP_002554.1, 5028, 18441 (mouse), 25265 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||42072 Da|
|Other Names||P2Y purinoceptor 1, P2Y1, ATP receptor, Purinergic receptor, P2RY1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||P2RY1 (aa345-356) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for extracellular adenine nucleotides such as ADP (PubMed:9442040, PubMed:9038354, PubMed:25822790). In platelets, binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and ultimately platelet aggregation (PubMed:9442040).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Calmodulin interacts with the platelet ADP receptor P2Y1. Arthur JF, Shen Y, Mu FT, Leon C, Gachet C, Berndt MC, Andrews RK. Biochem J. 2006 Sep 15;398(3):339-43. PMID: 16848759
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