|Other Accession||NP_001048.2, 6865|
|Calculated MW||44442 Da|
|Other Names||Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2, TACR2, NK2R, NKNAR, TAC2R|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TACR2 / Neurokinin 2 receptor Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NK2R, NKNAR, TAC2R|
|Function||This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Histopathology. 2007 Jul;51(1):128-31. Epub 2007 May 26. No abstract available. PMID: 17532769
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