|Application ||IHC, E|
|Other Accession||NP_001007099.1, NP_002970.2, NP_001180528.1, NP_001180529.1, NP_001180546.1, 6342, 20280 (mouse), 25541 (rat)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||58994 Da|
|Other Names||Non-specific lipid-transfer protein, NSL-TP, 220.127.116.11, Propanoyl-CoA C-acyltransferase, SCP-chi, SCPX, Sterol carrier protein 2, SCP-2, Sterol carrier protein X, SCP-X, SCP2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Sterol carrier protein 2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis.|
|Cellular Location||Cytoplasm. Mitochondrion. Note=Cytoplasmic in the liver and also associated with mitochondria especially in steroidogenic tissues Isoform SCP2: Mitochondrion.|
|Tissue Location||Liver, fibroblasts, and placenta.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform 1, 2, 6, 7 and 8 (NP_002970.2; NP_001007099.1; NP_001180529.1; NP_001180528.1; NP_001180546.1 respectively),
Sterol carrier protein-2 selectively alters lipid composition and cholesterol dynamics of caveolae/lipid raft vs nonraft domains in L-cell fibroblast plasma membranes. Atshaves BP, Gallegos AM, McIntosh AL, Kier AB, Schroeder F. Biochemistry. 2003 Dec 16;42(49):14583-98. PMID: 14661971
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