|Application ||WB, IHC, E|
|Other Accession||NP_001976.1, NP_001014763.1, 2109, 110826 (mouse), 292845 (rat)|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||27844 Da|
|Other Names||Electron transfer flavoprotein subunit beta, Beta-ETF, ETFB|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ETFB (aa 231-243) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Heterodimeric electron transfer flavoprotein that accepts electrons from several mitochondrial dehydrogenases, including acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase (PubMed:25416781, PubMed:15159392, PubMed:15975918). It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (Probable). Required for normal mitochondrial fatty acid oxidation and normal amino acid metabolism (PubMed:12815589, PubMed:7912128). ETFB binds an AMP molecule that probably has a purely structural role (PubMed:8962055, PubMed:15159392, PubMed:15975918).|
|Cellular Location||Mitochondrion matrix|
|Tissue Location||Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_001976.1; NP_001014763.1). Amino acid numbering in the name above refers to NP_001976.1).
Clinical and genetic analysis of lipid storage myopathies. Ohkuma A, Noguchi S, Sugie H, Malicdan MC, Fukuda T, Shimazu K, LÃ³pez LC, Hirano M, Hayashi YK, Nonaka I, Nishino I, Muscle & nerve 2009 Mar 39 (3): 333-42. PMID: 19208393
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