|Other Accession||NP_000802.2, 2559|
|Predicted||Human, Pig, Cow|
|Calculated MW||51024 Da|
|Other Names||Gamma-aminobutyric acid receptor subunit alpha-6, GABA(A) receptor subunit alpha-6, GABRA6|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GABRA6 (aa15-26) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
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Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder. Green EK, Grozeva D, Moskvina V, Hamshere ML, Jones IR, Jones L, Forty L, Caesar S, Gordon-Smith K, Fraser C, Russell E, St Clair D, Young AH, Ferrier N, Farmer A, McGuffin P, Holmans PA, Owen MJ, O'Donovan MC, Craddock N. Am J Med Genet B Neuropsychiatr Genet. 2010 Oct 5;153B(7):1347-9. PMID: 20583128
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