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RUVBL2 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • IHC - RUVBL2 antibody - N-terminal region AI10055
    RUVBL2 antibody - N-terminal region (AI10055) in Human Lung cells using Immunohistochemistry
    Human Lung
  • IHC - RUVBL2 antibody - N-terminal region AI10055
    RUVBL2 antibody - N-terminal region (AI10055) in Human urinary bladder cells using Immunohistochemistry
    Human urinary bladder
  • WB - RUVBL2 antibody - N-terminal region AI10055
    RUVBL2 antibody - N-terminal region (AI10055) in siRUVBL2 transfected H1299 cells using Western Blot
    Sample Type : Lane 1: 20ug untransfected H1299 cells Lane 2: 20ug siRUVBL2 transfected H1299 cells
    Primary Antibody Dilution : 1:1000
    Secondary Antibody: Anti-rabbit-HRP
    Secondary Antibody Dilution: 1:3000 Color/Signal Descriptions: RUVBL2 Gene Name: Wenwei Hu, Xuetian Yue, Rutgers Cancer Institute of New Jersey.
    Submitted by:
  • WB - RUVBL2 antibody - N-terminal region AI10055
    RUVBL2 antibody - N-terminal region (AI10055) in Human Daudi cells using Western Blot
    WB Suggested Anti-RUVBL2 Antibody Titration: 2.0-4.0μg/ml
    Positive Control: Daudi cell lysate
    RUVBL2 is supported by BioGPS gene expression data to be expressed in Daudi
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y230
Other Accession Q9Y230, NP_006657, NM_006666
Reactivity Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse, Bovine, Yeast
Predicted Mouse, Rat, Rabbit, Zebrafish, Pig, Dog, Guinea Pig, Horse
Host Rabbit
Clonality Polyclonal
Calculated MW 51 kDa
Additional Information
Gene ID 10856
Alias Symbol RVB2, TIH2, ECP51, TIP48, CGI-46, INO80J, REPTIN, TIP49B
Other Names RuvB-like 2, 48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, Repressing pontin 52, Reptin 52, TIP49b, TIP60-associated protein 54-beta, TAP54-beta, RUVBL2, INO80J, TIP48, TIP49B
Target/Specificity RuvB-Like 2 (48-kDa TATA box-binding protein-interacting protein, Reptin 52, RUVBL2) is the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this protein has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation.
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-RUVBL2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRUVBL2 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms INO80J, TIP48, TIP49B
Function Possesses single-stranded DNA-stimulated ATPase and ATP- dependent DNA helicase (5' to 3') activity; hexamerization is thought to be critical for ATP hydrolysis and adjacent subunits in the ring-like structure contribute to the ATPase activity. Proposed core component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and probably DNA repair. Involved in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway where it negatively regulates expression of ER stress response genes.
Cellular Location Nucleus matrix. Nucleus, nucleoplasm. Cytoplasm. Membrane. Note=Mainly localized in the nucleus, associated with nuclear matrix or in the nuclear cytosol. Although it is also present in the cytoplasm and associated with the cell membranes
Tissue Location Ubiquitously expressed. Highly expressed in testis and thymus
Research Areas
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This is a rabbit polyclonal antibody against RUVBL2. It was validated on Western Blot and immunohistochemistry by Abgent. At Abgent we manufacture rabbit polyclonal antibodies on a large scale (200-1000 products/month) of high throughput manner. Our antibodies are peptide based and protein family oriented. We usually provide antibodies covering each member of a whole protein family of your interest. We also use our best efforts to provide you antibodies recognize various epitopes of a target protein. For availability of antibody needed for your experiment, please inquire (

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$ 235.00
Cat# AI10055
Availability: 2-3 days
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