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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PRICKLE3 antibody - C-terminal region   

PRICKLE3 antibody - C-terminal region

Rabbit Polyclonal Antibody

     
  • WB - PRICKLE3 antibody - C-terminal region AI10642
    WB Suggested Anti-PRICKLE3 Antibody Titration: .2-1 μg/ml
    Positive Control: Transfected 293T
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O43900
Other Accession NM_006150, NP_006141
Reactivity Human, Mouse, Rat, Pig, Horse, Dog
Predicted Human, Mouse, Rat, Pig
Host Rabbit
Clonality Polyclonal
Calculated MW 68kDa
Additional Information
Gene ID 4007
Alias Symbol LMO6
Other Names Prickle-like protein 3, LIM domain only protein 6, LMO-6, Triple LIM domain protein 6, PRICKLE3, LMO6
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-PRICKLE3 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsPRICKLE3 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRICKLE3 (HGNC:6645)
Synonyms LMO6
Function Involved in the planar cell polarity (PCP) pathway that is essential for the polarization of epithelial cells during morphogenetic processes, including gastrulation and neurulation (By similarity). PCP is maintained by two molecular modules, the global and the core modules, PRICKLE3 being part of the core module (By similarity). Distinct complexes of the core module segregate to opposite sides of the cell, where they interact with the opposite complex in the neighboring cell at or near the adherents junctions (By similarity). Involved in the organization of the basal body (By similarity). Involved in cilia growth and positioning (By similarity).
Cellular Location Cytoplasm {ECO:0000250|UniProtKB:A8WH69}. Cell membrane {ECO:0000250|UniProtKB:A8WH69}; Peripheral membrane protein {ECO:0000250|UniProtKB:A8WH69}; Cytoplasmic side {ECO:0000250|UniProtKB:A8WH69}. Note=Recruited by VANGL2 to anterior cell borders. This polarity is controlled by Wnt proteins (By similarity). WTIP is involved in the recruitment of PRICKLE3 to the basal body (By similarity). {ECO:0000250|UniProtKB:A8WH69}
Tissue Location Widely expressed.
Research Areas
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References

Olsen,J.V., (2006) Cell 127 (3), 635-648 Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 295.00
Cat# AI10642
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