|Application ||WB, IHC|
|Other Accession||NM_005549, NP_005540|
|Reactivity||Human, Mouse, Rat, Bovine, Dog|
|Predicted||Mouse, Rat, Bovine|
|Alias Symbol||Kcn1, Kv1.8|
|Other Names||Potassium voltage-gated channel subfamily A member 10, Voltage-gated potassium channel subunit Kv1.8, KCNA10|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-KCNA10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||KCNA10 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Mediates voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. The channel activity is up-regulated by cAMP.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells.|
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Provided below are standard protocols that you may find useful for product applications.
Yao,X., et al., (2002) J. Am. Soc. Nephrol. 13 (12), 2831-2839Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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