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>   home   >   Products   >   Primary Antibodies   >   GATA5 antibody - C-terminal region   

GATA5 antibody - C-terminal region

Rabbit Polyclonal Antibody

  • WB - GATA5 antibody - C-terminal region AI11050

    WB Suggested Anti-GATA5 Antibody Titration: 1.25μg/ml
    ELISA Titer: 1:1562500
    Positive Control: SP2/0 cell lysate
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P97489
Other Accession NM_008093, NP_032119
Reactivity Mouse, Rat
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 44kDa
Additional Information
Other Names Transcription factor GATA-5, GATA-binding factor 5, Gata5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 100 ul of distilled water. Final anti-GATA5 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsGATA5 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Gata5 {ECO:0000312|MGI:MGI:109497}
Function Transcription factor required during cardiovascular development (By similarity). Plays an important role in the transcriptional program(s) that underlies smooth muscle cell diversity (PubMed:9119112). Binds to the functionally important CEF-1 nuclear protein binding site in the cardiac-specific slow/cardiac troponin C transcriptional enhancer (By similarity).
Cellular Location Nucleus. EMBL; U84725; AAB47506.1; -; mRNA EMBL; AK132020; BAE20945.1; -; mRNA EMBL; AK142213; BAE24979.1; -; mRNA EMBL; AL663027; CAM16220.1; -; Genomic_DNA EMBL; CH466626; EDL07330.1; -; Genomic_DNA CCDS; CCDS17175.1; - RefSeq; NP_032119.2; NM_008093.2 RefSeq; XP_006500617.1; XM_006500554.3 UniGene; Mm.388880; - ProteinModelPortal; P97489; - SMR; P97489; - BioGrid; 199842; 5 STRING; 10090.ENSMUSP00000015771; - iPTMnet; P97489; - PhosphoSitePlus; P97489; - MaxQB; P97489; - PaxDb; P97489; - PeptideAtlas; P97489; - PRIDE; P97489; - Ensembl; ENSMUST00000015771; ENSMUSP00000015771; ENSMUSG00000015627 GeneID; 14464; - KEGG; mmu:14464; - UCSC; uc008oix.2; mouse CTD; 140628; - MGI; MGI:109497; Gata5 eggNOG; KOG1601; Eukaryota eggNOG; COG5641; LUCA GeneTree; ENSGT00940000160139; - HOGENOM; HOG000047700; - HOVERGEN; HBG051703; - InParanoid; P97489; - KO; K17896; - OMA; WTAGPFD; - OrthoDB; 807790at2759; - TreeFam; TF315391; - Reactome; R-MMU-983231; Factors involved in megakaryocyte development and platelet production PRO; PR:P97489; - Proteomes; UP000000589; Chromosome 2 Bgee; ENSMUSG00000015627; Expressed in 67 organ(s), highest expression level in intestinal villus Genevisible; P97489; MM GO; GO:0000790; C:nuclear chromatin; IDA:BHF-UCL GO; GO:0005634; C:nucleus; ISO:MGI GO; GO:0003677; F:DNA binding; IDA:MGI GO; GO:0003700; F:DNA-binding transcription factor activity; ISO:MGI GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IDA:BHF-UCL GO; GO:0001158; F:enhancer sequence-specific DNA binding; IDA:UniProtKB GO; GO:0000978; F:RNA polymerase II proximal promoter sequence-specific DNA binding; IBA:GO_Central GO; GO:0044212; F:transcription regulatory region DNA binding; IDA:MGI GO; GO:0008270; F:zinc ion binding; IEA:InterPro GO; GO:0003180; P:aortic valve morphogenesis; IMP:BHF-UCL GO; GO:0048738; P:cardiac muscle tissue development; IBA:GO_Central GO; GO:0071773; P:cellular response to BMP stimulus; IDA:MGI GO; GO:0072359; P:circulatory system development; IBA:GO_Central GO; GO:0003274; P:endocardial cushion fusion; IMP:BHF-UCL GO; GO:0060575; P:intestinal epithelial cell differentiation; ISO:MGI GO; GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:BHF-UCL GO; GO:0010629; P:negative regulation of gene expression; IMP:BHF-UCL GO; GO:0062000; P:positive regulation of cardiac endothelial to mesenchymal transition; IMP:BHF-UCL GO; GO:0010628; P:positive regulation of gene expression; IMP:BHF-UCL GO; GO:0035481; P:positive regulation of Notch signaling pathway involved in heart induction; IMP:BHF-UCL GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; ISO:MGI GO; GO:1901228; P:positive regulation of transcription from RNA polymerase II promoter involved in heart development; IDA:BHF-UCL GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:MGI GO; GO:0006355; P:regulation of transcription, DNA-templated; IDA:MGI CDD; cd00202; ZnF_GATA; 2 Gene3D;; -; 2 InterPro; IPR008013; GATA_N InterPro; IPR016375; TF_GATA_4/5/6 InterPro; IPR039355; Transcription_factor_GATA InterPro; IPR000679; Znf_GATA InterPro; IPR013088; Znf_NHR/GATA PANTHER; PTHR10071; PTHR10071; 1 Pfam; PF00320; GATA; 2 Pfam; PF05349; GATA-N; 1 PIRSF; PIRSF003028; TF_GATA_4/5/6; 1 PRINTS; PR00619; GATAZNFINGER SMART; SM00401; ZnF_GATA; 2 PROSITE; PS00344; GATA_ZN_FINGER_1; 2 PROSITE; PS50114; GATA_ZN_FINGER_2; 2 1: Evidence at protein level; Activator; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger CHAIN 1 404 Transcription factor GATA-5 /FTId=PRO_0000083419 ZN_FING 196 220 GATA-type 1. {ECO:0000255|PROSITE- ProRule:PRU00094} ZN_FING 250 274 GATA-type 2. {ECO:0000255|PROSITE- ProRule:PRU00094} CONFLICT 67 67 A -> T (in Ref. 1; AAB47506) CONFLICT 302 302 K -> E (in Ref. 1; AAB47506) SEQUENCE 404 AA; 42114 MW; 6C0990A85D594F0C CRC64; MYQSLALAQS PGQGTYADSG AFLHSSGTGS PVFVAPTRMP SMLPYLPSCE PGSQAPALAA HSSWTQAVAA DSSAFGSGSP HPPAAHPPGA TTFPFAHSPP GSGSGGSAGV RDGGAFQGAL LAREQYPTPL GRPMGASYPT TYPAYMSSDV APSWTSGAFD SSILHGLQAR PGGLPGRRTS FVPDFLEEFP GEGRECVNCG ALSTPLWRRD GTGHYLCNAC GLYHKMNGVN RPLVRPQKRL SSSRRSGLCC SNCHTATTTL WRRNSEGEPV CNACGLYMKL HGVPRPLAMK KESIQTRKRK PKNPAKIKGS SGSTANTTAS SPTLLNSESS ATTLKAESSL ASPVCAGPTI TSQASSPADE SLASSHLEFK FEPEDFAFTS SSMSPQAGLS GVLRQETWCA LALA
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Mermod,N., et al., (2005) Mol. Cell. Biol. 25 (24), 10953-10964Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.

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$ 235.00
Cat# AI11050
Availability: 2-3 days
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