|Other Accession||NM_008718, NP_032744|
|Alias Symbol||MOP5, bHLHe11|
|Other Names||Neuronal PAS domain-containing protein 1, Neuronal PAS1, Npas1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Npas1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Npas1 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May control regulatory pathways relevant to schizophrenia and to psychotic illness. May play a role in late central nervous system development by modulating EPO expression in response to cellular oxygen level. Forms a heterodimer that binds core DNA sequence 5'-TACGTG-3' within the hypoxia response element (HRE) leading to transcriptional repression on its target gene TH (PubMed:27782878).|
|Tissue Location||Expressed in brain in inhibitory interneurons. Also found in spinal cord.|
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