|Other Accession||NM_001025562, NP_001020733|
|Alias Symbol||A730013B20Rik, MPUS1, mPus1p|
|Other Names||tRNA pseudouridine synthase A, mitochondrial, 22.214.171.124, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA-uridine isomerase I, Pus1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Pus1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Pus1 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Converts specific uridines to PSI in a number of tRNA substrates. Acts on positions 27/28 in the anticodon stem and also positions 34 and 36 in the anticodon of an intron containing tRNA (PubMed:10094309). Involved in regulation of nuclear receptor activity possibly through pseudouridylation of SRA1 RNA (PubMed:15327771). Isoforms 3 and 4 do not form pseudouridine when expressed in vitro (PubMed:11085940).|
|Cellular Location||Isoform 1: Mitochondrion.|
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