|Other Accession||NM_009880, NP_034010|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Horse, Bovine, Dog|
|Predicted||Mouse, Rat, Rabbit, Zebrafish, Chicken, Bovine|
|Alias Symbol||Cdx, Cdx-1|
|Other Names||Homeobox protein CDX-1, Caudal-type homeobox protein 1, Cdx1, Cdx-1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-Cdx1 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||Cdx1 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in transcriptional regulation. Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells. Binds to the PRKD1 promoter in colorectal cancer (CRC) cells. Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA.|
|Tissue Location||Intestinal epithelium.|
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