|Application ||WB, IHC|
|Other Accession||NM_182976, NP_892021|
|Reactivity||Human, Rat, Dog|
|Alias Symbol||FLJ20403, MGC61591, ZAN75, Zfp326, dJ871E2.1|
|Other Names||DBIRD complex subunit ZNF326, Zinc finger protein 326, Zinc finger protein interacting with mRNPs and DBC1, ZNF326, ZIRD|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-ZNF326 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||ZNF326 antibody - C-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Core component of the DBIRD complex, a multiprotein complex that acts at the interface between core mRNP particles and RNA polymerase II (RNAPII) and integrates transcript elongation with the regulation of alternative splicing: the DBIRD complex affects local transcript elongation rates and alternative splicing of a large set of exons embedded in (A + T)-rich DNA regions. May play a role in neuronal differentiation and is able to bind DNA and activate expression in vitro.|
|Cellular Location||Nucleus matrix.|
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Provided below are standard protocols that you may find useful for product applications.
Strausberg,R.L., (2002) Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903Reconstitution and Storage:For short term use, store at 2-8C up to 1 week. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles.
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