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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Wdr8 antibody - N-terminal region   

Wdr8 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Wdr8 antibody - N-terminal region AI11873

    WB Suggested Anti-Wdr8 Antibody Titration: 1.0 μg/ml
    Positive Control: Mouse Brain
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9JM98
Other Accession NM_021499, NP_067474
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Chicken
Host Rabbit
Clonality Polyclonal
Calculated MW 52kDa
Additional Information
Alias Symbol 2610044M17Rik, 5330425N03Rik, Dd57, Wrap73, Wdr8
Other Names WD repeat-containing protein WRAP73, WD repeat-containing protein 8, WD repeat-containing protein antisense to TP73 gene, Wrap73, Dd57, Wdr8
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Wdr8 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsWdr8 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Wrap73
Synonyms Dd57, Wdr8
Function The SSX2IP:WRAP73 complex is proposed to act as regulator of spindle anchoring at the mitotic centrosome. Required for the centrosomal localization of SSX2IP and normal mitotic bipolar spindle morphology. Required for the targeting of centriole satellite proteins to centrosomes such as of PCM1, SSX2IP, CEP290 and PIBF1/CEP90. Required for ciliogenesis and involved in the removal of the CEP97:CCP110 complex from the mother centriole. Involved in ciliary vesicle formation at the mother centriole and required for the docking of vesicles to the basal body during ciliogenesis; may promote docking of RAB8A- and ARL13B-containing vesicles (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250|UniProtKB:Q9P2S5}. Note=Enriched in the proximal end of the mother centriole. During ciliogenesis also associated with the basal body of the adjacent centriole (By similarity) {ECO:0000250|UniProtKB:Q9P2S5}
Tissue Location Ubiquitous. EMBL; AB034911; BAA92311.1; -; mRNA EMBL; AK051688; BAC34722.1; -; mRNA EMBL; AK156969; BAE33920.1; -; mRNA EMBL; AK160331; BAE35741.1; -; mRNA EMBL; AL806525; CAM18777.1; -; Genomic_DNA EMBL; CH466594; EDL14958.1; -; Genomic_DNA CCDS; CCDS19010.1; - RefSeq; NP_067474.2; NM_021499.2 UniGene; Mm.46508; - ProteinModelPortal; Q9JM98; - IntAct; Q9JM98; 2 STRING; 10090.ENSMUSP00000030895; - PhosphoSitePlus; Q9JM98; - MaxQB; Q9JM98; - PaxDb; Q9JM98; - PRIDE; Q9JM98; - Ensembl; ENSMUST00000030895; ENSMUSP00000030895; ENSMUSG00000029029 GeneID; 59002; - KEGG; mmu:59002; - UCSC; uc008wbi.1; mouse CTD; 49856; - MGI; MGI:1891749; Wrap73 eggNOG; KOG4497; Eukaryota eggNOG; ENOG410Y2P7; LUCA GeneTree; ENSGT00390000003623; - HOGENOM; HOG000243586; - HOVERGEN; HBG022803; - InParanoid; Q9JM98; - OMA; YSAYEWS; - OrthoDB; 764000at2759; - TreeFam; TF329103; - PRO; PR:Q9JM98; - Proteomes; UP000000589; Chromosome 4 Bgee; ENSMUSG00000029029; Expressed in 260 organ(s), highest expression level in pancreas ExpressionAtlas; Q9JM98; baseline and differential Genevisible; Q9JM98; MM GO; GO:0005813; C:centrosome; ISO:MGI GO; GO:0036064; C:ciliary basal body; ISS:UniProtKB GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell GO; GO:0030030; P:cell projection organization; IEA:UniProtKB-KW GO; GO:0090307; P:mitotic spindle assembly; ISO:MGI GO; GO:1902857; P:positive regulation of non-motile cilium assembly; ISS:UniProtKB Gene3D;; -; 3 InterPro; IPR011044; Quino_amine_DH_bsu InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf InterPro; IPR001680; WD40_repeat Pfam; PF00400; WD40; 1 SMART; SM00320; WD40; 4 SUPFAM; SSF50969; SSF50969; 1 1: Evidence at protein level; Cilium biogenesis/degradation; Complete proteome; Cytoplasm; Cytoskeleton; Phosphoprotein; Reference proteome; Repeat; WD repeat CHAIN 1 462 WD repeat-containing protein WRAP73 /FTId=PRO_0000051357 REPEAT 46 86 WD 1 REPEAT 89 129 WD 2 REPEAT 176 210 WD 3 REPEAT 221 260 WD 4 REPEAT 328 369 WD 5 REPEAT 371 410 WD 6 MOD_RES 281 281 Phosphoserine {ECO:0000250|UniProtKB:Q9P2S5} CONFLICT 417 417 P -> A (in Ref. 1; BAA92311) SEQUENCE 462 AA; 52053 MW; 6A32524BB1945845 CRC64; MNFSESFKLS GLLCRFSPDG KYLASCVQYR LVIRDVTTLQ ILQLYTCLDQ IQHIEWSADS LFILCAMYRR GLVQVWSLEQ PEWHCKIDEG SAGLVASCWS PDGRHILNTT EFHLRITVWS LCTKSVSYIK YPKACQQGLT FTRDGRYLAL AERRDCRDYV SIFVCSDWQL LRHFDTDTQD LTGIEWAPNG CVLAAWDTCL EYKVLLYSLD GRLLSAYCAY EWSLGIKSVA WSPSSQFLAI GSYDGKVRLL NHVTWKMITE FGHPATINNP KTVVYKEAEK SPLLGLGHLS FPPPRAMAGA LSTSESKYEI ASGPVSLQTL KPVADRANPR MGVGMLAFSS DSYFLASRND NVPNAVWIWD IQKLKLFVVL EHMSPVRSFQ WDPQQPRLAI CTGGSKVYLW SPAGCVSVQV PGEGDFPVLG LCWHLSGDSL ALLSKDHFCL CFLETKERVG TAYEQRDGMP RT
Research Areas
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$ 295.00
Cat# AI11873
Availability: 2-3 days
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