|Other Accession||NM_004437, NP_004428|
|Reactivity||Human, Mouse, Rat, Rabbit, Pig, Horse, Yeast, Bovine|
|Predicted||Human, Rabbit, Pig, Horse|
|Alias Symbol||4.1R, EL1, HE|
|Other Names||Protein 4.1, P4.1, 4.1R, Band 4.1, EPB4.1, EPB41, E41P|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 50 ul of distilled water. Final anti-EPB41 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||EPB41 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protein 4.1 is a major structural element of the erythrocyte membrane skeleton. It plays a key role in regulating membrane physical properties of mechanical stability and deformability by stabilizing spectrin-actin interaction. Recruits DLG1 to membranes. Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase (PubMed:23870127).|
|Cellular Location||Cytoplasm, cytoskeleton. Cytoplasm, cell cortex Nucleus|
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