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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rgs18 antibody - N-terminal region   

Rgs18 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • WB - Rgs18 antibody - N-terminal region AI12168

    WB Suggested Anti-Rgs18 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:312500
    Positive Control: Mouse Lung
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession Q99PG4
Other Accession NM_022881, NP_075019
Reactivity Mouse, Rat
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Calculated MW 27kDa
Additional Information
Alias Symbol MGC117531
Other Names Regulator of G-protein signaling 18, RGS18, Rgs18
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rgs18 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRgs18 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rgs18
Function Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G(i) alpha-1, G(i) alpha- 2, G(i) alpha-3 and G(q) alpha.
Cellular Location Cytoplasm.
Tissue Location Expressed in bone marrow, spleen, fetal liver and lung. At very low levels expressed in heart EMBL; AF302685; AAG53657.1; -; mRNA EMBL; AB042807; BAB60723.1; -; mRNA CCDS; CCDS15350.1; - RefSeq; NP_075019.1; NM_022881.4 UniGene; Mm.253927; - ProteinModelPortal; Q99PG4; - SMR; Q99PG4; - BioGrid; 211040; 2 STRING; 10090.ENSMUSP00000027603; - iPTMnet; Q99PG4; - PhosphoSitePlus; Q99PG4; - jPOST; Q99PG4; - MaxQB; Q99PG4; - PaxDb; Q99PG4; - PRIDE; Q99PG4; - Ensembl; ENSMUST00000027603; ENSMUSP00000027603; ENSMUSG00000026357 GeneID; 64214; - KEGG; mmu:64214; - UCSC; uc007cxl.1; mouse CTD; 64407; - MGI; MGI:1927498; Rgs18 eggNOG; KOG3589; Eukaryota eggNOG; ENOG410YMJD; LUCA GeneTree; ENSGT00940000161034; - HOGENOM; HOG000233512; - HOVERGEN; HBG013233; - InParanoid; Q99PG4; - KO; K16449; - OMA; LNMCESK; - OrthoDB; 1193829at2759; - PhylomeDB; Q99PG4; - TreeFam; TF315837; - Reactome; R-MMU-416476; G alpha (q) signalling events Reactome; R-MMU-418594; G alpha (i) signalling events ChiTaRS; Rgs18; mouse PRO; PR:Q99PG4; - Proteomes; UP000000589; Chromosome 1 Bgee; ENSMUSG00000026357; Expressed in 89 organ(s), highest expression level in blood ExpressionAtlas; Q99PG4; baseline and differential Genevisible; Q99PG4; MM GO; GO:0005737; C:cytoplasm; IDA:MGI GO; GO:0005096; F:GTPase activator activity; IDA:MGI GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IPI:MGI GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW GO; GO:0008277; P:regulation of G protein-coupled receptor signaling pathway; IDA:MGI Gene3D; 1.10.196.10; -; 2 InterPro; IPR016137; RGS InterPro; IPR034950; RGS18 InterPro; IPR036305; RGS_sf InterPro; IPR024066; RGS_subdom1/3 PANTHER; PTHR10845:SF155; PTHR10845:SF155; 1 Pfam; PF00615; RGS; 1 PRINTS; PR01301; RGSPROTEIN SMART; SM00315; RGS; 1 SUPFAM; SSF48097; SSF48097; 1 PROSITE; PS50132; RGS; 1 1: Evidence at protein level; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Signal transduction inhibitor CHAIN 1 235 Regulator of G-protein signaling 18 /FTId=PRO_0000204228 DOMAIN 86 202 RGS. {ECO:0000255|PROSITE- ProRule:PRU00171} MOD_RES 49 49 Phosphoserine {ECO:0000250|UniProtKB:Q9NS28} MOD_RES 216 216 Phosphoserine MOD_RES 218 218 Phosphoserine SEQUENCE 235 AA; 27610 MW; 6433435AC1CBCFD8 CRC64; MDMSLVFFSQ LNMCESKEKT FFKLMHGSGK EETSIEAKIR AKEKRNRLSL LLQRPDFHGE TQASRSALLA KETRVSPEEA VKWAESFDKL LSHRDGVDAF TRFLKTEFSE ENIEFWVACE DFKKCKEPQQ IILKAKAIYE KFIQNDAPKE VNIDFHTKEV IAKSIAQPTL HSFDTAQSRV YQLMEHDSYK RFLKSETYLH LIEGRPQRPT NLRRRSRSFT YNDFQDVKSD VAIWL
Research Areas
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$ 295.00
Cat# AI12168
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