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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Rgs10 antibody - N-terminal region   

Rgs10 antibody - N-terminal region

Rabbit Polyclonal Antibody

  • WB - Rgs10 antibody - N-terminal region AI12169

    WB Suggested Anti-Rgs10 Antibody Titration: 0.2-1 μg/ml
    ELISA Titer: 1:1562500
    Positive Control: Mouse Thymus
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9CQE5
Other Accession NM_026418, NP_080694
Reactivity Human, Mouse, Rat, Pig, Bovine
Predicted Human, Mouse, Rat, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 21kDa
Additional Information
Alias Symbol 2310010N19Rik, MGC129414
Other Names Regulator of G-protein signaling 10, RGS10, Rgs10
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-Rgs10 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsRgs10 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Rgs10
Function Regulates G protein-coupled receptor signaling cascades, including signaling downstream of the muscarinic acetylcholine receptor CHRM2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Modulates the activity of potassium channels that are activated in response to CHRM2 signaling. Activity on GNAZ is inhibited by palmitoylation of the G-protein.
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:O43665}. Nucleus {ECO:0000250|UniProtKB:O43665}. Note=Forskolin treatment promotes phosphorylation and translocation to the nucleus {ECO:0000250|UniProtKB:O43665} EMBL; AK009686; BAB26440.1; -; mRNA EMBL; AK009283; BAB26193.1; -; mRNA EMBL; AK017314; BAB30688.1; -; mRNA EMBL; AK088009; BAC40091.1; -; mRNA CCDS; CCDS21896.1; - RefSeq; NP_080694.1; NM_026418.2 UniGene; Mm.18635; - ProteinModelPortal; Q9CQE5; - SMR; Q9CQE5; - IntAct; Q9CQE5; 1 MINT; Q9CQE5; - STRING; 10090.ENSMUSP00000033133; - iPTMnet; Q9CQE5; - PhosphoSitePlus; Q9CQE5; - EPD; Q9CQE5; - MaxQB; Q9CQE5; - PaxDb; Q9CQE5; - PRIDE; Q9CQE5; - Ensembl; ENSMUST00000033133; ENSMUSP00000033133; ENSMUSG00000030844 GeneID; 67865; - KEGG; mmu:67865; - UCSC; uc009jyw.1; mouse CTD; 6001; - MGI; MGI:1915115; Rgs10 eggNOG; KOG3589; Eukaryota eggNOG; ENOG410YMJD; LUCA GeneTree; ENSGT00760000119142; - HOGENOM; HOG000233512; - HOVERGEN; HBG013233; - InParanoid; Q9CQE5; - KO; K16449; - OMA; PKSTAKW; - OrthoDB; EOG091G0BDG; - PhylomeDB; Q9CQE5; - TreeFam; TF315837; - PRO; PR:Q9CQE5; - Proteomes; UP000000589; Chromosome 7 Bgee; ENSMUSG00000030844; - CleanEx; MM_RGS10; - ExpressionAtlas; Q9CQE5; baseline and differential Genevisible; Q9CQE5; MM GO; GO:0043679; C:axon terminus; ISO:MGI GO; GO:0005737; C:cytoplasm; IBA:GO_Central GO; GO:0005829; C:cytosol; ISS:UniProtKB GO; GO:0043197; C:dendritic spine; ISO:MGI GO; GO:0043025; C:neuronal cell body; ISO:MGI GO; GO:0005634; C:nucleus; ISS:UniProtKB GO; GO:0005886; C:plasma membrane; IBA:GO_Central GO; GO:0001965; F:G-protein alpha-subunit binding; ISO:MGI GO; GO:0005096; F:GTPase activator activity; ISS:UniProtKB GO; GO:0007213; P:G-protein coupled acetylcholine receptor signaling pathway; ISS:UniProtKB GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW GO; GO:0043547; P:positive regulation of GTPase activity; ISS:UniProtKB GO; GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IEA:InterPro GO; GO:0001975; P:response to amphetamine; IEA:Ensembl CDD; cd08741; RGS_RGS10; 1 Gene3D;; -; 2 InterPro; IPR016137; RGS InterPro; IPR037879; RGS10_RGS InterPro; IPR036305; RGS_sf InterPro; IPR024066; RGS_subdom1/3 Pfam; PF00615; RGS; 1 PRINTS; PR01301; RGSPROTEIN SMART; SM00315; RGS; 1 SUPFAM; SSF48097; SSF48097; 1 PROSITE; PS50132; RGS; 1 1: Evidence at protein level; Complete proteome; Cytoplasm; GTPase activation; Lipoprotein; Nucleus; Palmitate; Phosphoprotein; Reference proteome; Signal transduction inhibitor CHAIN 1 181 Regulator of G-protein signaling 10 /FTId=PRO_0000204208 DOMAIN 41 156 RGS. {ECO:0000255|PROSITE- ProRule:PRU00171} MOD_RES 41 41 Phosphoserine MOD_RES 176 176 Phosphoserine {ECO:0000250|UniProtKB:O43665} LIPID 74 74 S-palmitoyl cysteine {ECO:0000250|UniProtKB:O43665} CONFLICT 73 73 A -> E (in Ref. 1; BAB30688) SEQUENCE 181 AA; 21151 MW; 9897860505962286 CRC64; MFTRAVSRLS RKRPPSDIHD GDGSSSSGHQ SLKSTAKWAS SLENLLEDPE GVQRFREFLK KEFSEENVLF WLACEDFKKT EDRKQMQEKA KEIYMTFLSN KASSQVNVEG QSRLTEKILE EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKPKRTEE EEEEPPDAQT AAKRASRIYN T
Research Areas
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$ 295.00
Cat# AI12169
Availability: 2-3 days
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