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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   LRRN2 antibody - middle region   

LRRN2 antibody - middle region

Rabbit Polyclonal Antibody

     
  • WB - LRRN2 antibody - middle region AI12706

    WB Suggested Anti-LRRN2 Antibody Titration: 0.2-1 μg/ml
    Positive Control: THP-1 cell lysate
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession O75325
Other Accession NM_006338, NP_006329
Reactivity Human, Mouse, Rat, Pig, Horse, Bovine, Dog
Predicted Human, Mouse, Rat, Horse, Bovine
Host Rabbit
Clonality Polyclonal
Calculated MW 79kDa
Additional Information
Alias Symbol FIGLER7, GAC1, LRANK1, LRRN5
Other Names Leucine-rich repeat neuronal protein 2, Glioma amplified on chromosome 1 protein, Leucine-rich repeat neuronal protein 5, LRRN2, GAC1, LRRN5
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-LRRN2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsLRRN2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LRRN2
Synonyms GAC1, LRRN5
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Overamplified in malignant gliomas. EMBL; AF030435; AAC39792.1; -; mRNA EMBL; AY358290; AAQ88657.1; -; mRNA EMBL; AK312408; BAG35321.1; -; mRNA EMBL; AL512306; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; CH471067; EAW91520.1; -; Genomic_DNA EMBL; BC034047; AAH34047.1; -; mRNA EMBL; BC068541; AAH68541.1; -; mRNA CCDS; CCDS1448.1; - RefSeq; NP_006329.2; NM_006338.2 RefSeq; NP_963924.1; NM_201630.1 RefSeq; XP_005244884.1; XM_005244827.3 RefSeq; XP_011507368.1; XM_011509066.2 RefSeq; XP_016855539.1; XM_017000050.1 UniGene; Hs.26312; - ProteinModelPortal; O75325; - SMR; O75325; - BioGrid; 115711; 18 IntAct; O75325; 1 STRING; 9606.ENSP00000356143; - iPTMnet; O75325; - PhosphoSitePlus; O75325; - BioMuta; LRRN2; - MaxQB; O75325; - PaxDb; O75325; - PeptideAtlas; O75325; - PRIDE; O75325; - ProteomicsDB; 49895; - DNASU; 10446; - Ensembl; ENST00000367175; ENSP00000356143; ENSG00000170382 Ensembl; ENST00000367176; ENSP00000356144; ENSG00000170382 Ensembl; ENST00000367177; ENSP00000356145; ENSG00000170382 GeneID; 10446; - KEGG; hsa:10446; - UCSC; uc001hbe.3; human CTD; 10446; - DisGeNET; 10446; - EuPathDB; HostDB:ENSG00000170382.11; - GeneCards; LRRN2; - H-InvDB; HIX0001502; - HGNC; HGNC:16914; LRRN2 HPA; HPA029124; - MIM; 605492; gene neXtProt; NX_O75325; - OpenTargets; ENSG00000170382; - PharmGKB; PA162394661; - eggNOG; KOG0619; Eukaryota eggNOG; COG4886; LUCA GeneTree; ENSGT00760000118831; - HOGENOM; HOG000252914; - HOVERGEN; HBG052361; - InParanoid; O75325; - OMA; TEYWACL; - OrthoDB; EOG091G066E; - PhylomeDB; O75325; - TreeFam; TF334360; - ChiTaRS; LRRN2; human GeneWiki; LRRN2; - GenomeRNAi; 10446; - PRO; PR:O75325; - Proteomes; UP000005640; Chromosome 1 Bgee; ENSG00000170382; - CleanEx; HS_LRRN2; - ExpressionAtlas; O75325; baseline and differential Genevisible; O75325; HS GO; GO:0005615; C:extracellular space; IBA:GO_Central GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW GO; GO:0038023; F:signaling receptor activity; TAS:ProtInc GO; GO:0007409; P:axonogenesis; IBA:GO_Central GO; GO:0007155; P:cell adhesion; TAS:ProtInc GO; GO:0007165; P:signal transduction; TAS:ProtInc Gene3D; 2.60.40.10; -; 1 Gene3D; 3.80.10.10; -; 2 InterPro; IPR000483; Cys-rich_flank_reg_C InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR013098; Ig_I-set InterPro; IPR003599; Ig_sub InterPro; IPR003598; Ig_sub2 InterPro; IPR001611; Leu-rich_rpt InterPro; IPR003591; Leu-rich_rpt_typical-subtyp InterPro; IPR032675; LRR_dom_sf Pfam; PF07679; I-set; 1 Pfam; PF13855; LRR_8; 3 SMART; SM00409; IG; 1 SMART; SM00408; IGc2; 1 SMART; SM00369; LRR_TYP; 10 SMART; SM00082; LRRCT; 1 SUPFAM; SSF48726; SSF48726; 1 PROSITE; PS50835; IG_LIKE; 1 PROSITE; PS51450; LRR; 9 2: Evidence at transcript level; Complete proteome; Disulfide bond; Glycoprotein; Immunoglobulin domain; Leucine-rich repeat; Membrane; Polymorphism; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 18 CHAIN 19 713 Leucine-rich repeat neuronal protein 2 /FTId=PRO_0000014849 TOPO_DOM 19 630 Extracellular. TRANSMEM 631 651 Helical. TOPO_DOM 652 713 Cytoplasmic. DOMAIN 20 69 LRRNT REPEAT 70 91 LRR 1 REPEAT 94 115 LRR 2 REPEAT 118 139 LRR 3 REPEAT 142 163 LRR 4 REPEAT 166 187 LRR 5 REPEAT 190 211 LRR 6 REPEAT 214 235 LRR 7 REPEAT 238 259 LRR 8 REPEAT 262 283 LRR 9 REPEAT 286 305 LRR 10 REPEAT 311 333 LRR 11 REPEAT 336 357 LRR 12 DOMAIN 369 422 LRRCT DOMAIN 422 511 Ig-like C2-type CARBOHYD 94 94 N-linked (GlcNAc...) asparagine CARBOHYD 381 381 N-linked (GlcNAc...) asparagine CARBOHYD 555 555 N-linked (GlcNAc...) asparagine CARBOHYD 583 583 N-linked (GlcNAc...) asparagine DISULFID 445 497 {ECO:0000255|PROSITE-ProRule:PRU00114} VARIANT 7 7 P -> L (in dbSNP:rs3789044) /FTId=VAR_021921 VARIANT 19 19 A -> T (in dbSNP:rs36012907) /FTId=VAR_049898 VARIANT 518 518 L -> V (in dbSNP:rs3747631) /FTId=VAR_021922 VARIANT 659 659 V -> A (in dbSNP:rs34771052) /FTId=VAR_049899 VARIANT 692 692 P -> S (in dbSNP:rs11588857) /FTId=VAR_049900 CONFLICT 355 355 V -> A (in Ref. 6; AAH34047/AAH68541) CONFLICT 474 474 Y -> C (in Ref. 1; AAC39792) CONFLICT 676 676 A -> P (in Ref. 6; AAH34047/AAH68541) SEQUENCE 713 AA; 78859 MW; 8B97B131FF61254A CRC64; MRLLVAPLLL AWVAGATAAV PVVPWHVPCP PQCACQIRPW YTPRSSYREA TTVDCNDLFL TAVPPALPAG TQTLLLQSNS IVRVDQSELG YLANLTELDL SQNSFSDARD CDFHALPQLL SLHLEENQLT RLEDHSFAGL ASLQELYLNH NQLYRIAPRA FSGLSNLLRL HLNSNLLRAI DSRWFEMLPN LEILMIGGNK VDAILDMNFR PLANLRSLVL AGMNLREISD YALEGLQSLE SLSFYDNQLA RVPRRALEQV PGLKFLDLNK NPLQRVGPGD FANMLHLKEL GLNNMEELVS IDKFALVNLP ELTKLDITNN PRLSFIHPRA FHHLPQMETL MLNNNALSAL HQQTVESLPN LQEVGLHGNP IRCDCVIRWA NATGTRVRFI EPQSTLCAEP PDLQRLPVRE VPFREMTDHC LPLISPRSFP PSLQVASGES MVLHCRALAE PEPEIYWVTP AGLRLTPAHA GRRYRVYPEG TLELRRVTAE EAGLYTCVAQ NLVGADTKTV SVVVGRALLQ PGRDEGQGLE LRVQETHPYH ILLSWVTPPN TVSTNLTWSS ASSLRGQGAT ALARLPRGTH SYNITRLLQA TEYWACLQVA FADAHTQLAC VWARTKEATS CHRALGDRPG LIAILALAVL LLAAGLAAHL GTGQPRKGVG GRRPLPPAWA FWGWSAPSVR VVSAPLVLPW NPGRKLPRSS EGETLLPPLS QNS
Research Areas
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$ 295.00
Cat# AI12706
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