|Application ||WB, IHC|
|Other Accession||NM_014607, NP_055422|
|Reactivity||Human, Mouse, Rat, Rabbit, Zebrafish, Pig, Goat, Horse, Bovine, Guinea Pig, Dog|
|Alias Symbol||FLJ23318, KIAA0242, UBXDC1, erasin, UBXD2|
|Other Names||UBX domain-containing protein 4, Erasin, UBX domain-containing protein 2, UBXN4, KIAA0242, UBXD2, UBXDC1|
|Format||Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.|
|Reconstitution & Storage||Add 100 ul of distilled water. Final anti-UBXD2 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.|
|Precautions||UBXD2 antibody - middle region is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA0242, UBXD2, UBXDC1|
|Function||Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD (PubMed:19822669).|
|Cellular Location||Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope. Note=Both the N- and the C-terminus face the cytosol. Also found in the nucleus envelope contiguous to the ER.|
|Tissue Location||Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).|
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