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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   NTN4 antibody - N-terminal region   

NTN4 antibody - N-terminal region

Rabbit Polyclonal Antibody

     
  • IHC - NTN4 antibody - N-terminal region AI13058
    rat and mouse brain
  • WB - NTN4 antibody - N-terminal region AI13058

    WB Suggested Anti-NTN4 Antibody Titration: 0.2-1 μg/ml
    Positive Control: MCF7 cell lysate
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC
Primary Accession Q9HB63
Other Accession NM_021229, NP_067052
Reactivity Human, Mouse, Rat, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Predicted Human, Mouse, Rabbit, Pig, Horse, Bovine, Guinea Pig, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 70kDa
Additional Information
Alias Symbol FLJ23180, PRO3091
Other Names Netrin-4, Beta-netrin, Hepar-derived netrin-like protein, NTN4
Format Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Reconstitution & Storage Add 50 ul of distilled water. Final anti-NTN4 antibody concentration is 1 mg/ml in PBS buffer with 2% sucrose. For longer periods of storage, store at 20°C. Avoid repeat freeze-thaw cycles.
PrecautionsNTN4 antibody - N-terminal region is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NTN4
Function May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants.
Cellular Location Secreted, extracellular space, extracellular matrix, basement membrane Note=Major component
Tissue Location Expressed in kidney, spleen, mammary gland, aorta, heart, ovary, prostate and fetal spleen EMBL; AF278532; AAG30822.1; -; mRNA EMBL; AF297711; AAG53651.1; -; mRNA EMBL; AF119916; AAF69670.2; -; mRNA EMBL; AY330211; AAP92113.1; -; mRNA EMBL; AL137540; CAB70800.3; -; mRNA EMBL; CH471054; EAW97544.1; -; Genomic_DNA EMBL; BC013591; AAH13591.2; -; mRNA EMBL; BC136798; AAI36799.1; -; mRNA EMBL; BC136799; AAI36800.1; -; mRNA EMBL; AL833767; CAH56243.1; -; mRNA EMBL; AK024691; BAB14964.1; -; mRNA CCDS; CCDS9054.1; -. [Q9HB63-1] PIR; T46383; T46383 RefSeq; NP_001316629.1; NM_001329700.1. [Q9HB63-2] RefSeq; NP_001316630.1; NM_001329701.1. [Q9HB63-3] RefSeq; NP_001316631.1; NM_001329702.1. [Q9HB63-3] RefSeq; NP_067052.2; NM_021229.3. [Q9HB63-1] UniGene; Hs.201034; - ProteinModelPortal; Q9HB63; - SMR; Q9HB63; - BioGrid; 121866; 8 DIP; DIP-46274N; - IntAct; Q9HB63; 19 MINT; Q9HB63; - STRING; 9606.ENSP00000340998; - iPTMnet; Q9HB63; - PhosphoSitePlus; Q9HB63; - BioMuta; NTN4; - DMDM; 76789662; - MaxQB; Q9HB63; - PaxDb; Q9HB63; - PeptideAtlas; Q9HB63; - PRIDE; Q9HB63; - ProteomicsDB; 81495; - ProteomicsDB; 81496; -. [Q9HB63-2] ProteomicsDB; 81497; -. [Q9HB63-3] Ensembl; ENST00000343702; ENSP00000340998; ENSG00000074527. [Q9HB63-1] Ensembl; ENST00000344911; ENSP00000339436; ENSG00000074527. [Q9HB63-3] Ensembl; ENST00000538383; ENSP00000444432; ENSG00000074527. [Q9HB63-3] Ensembl; ENST00000553059; ENSP00000447292; ENSG00000074527. [Q9HB63-2] GeneID; 59277; - KEGG; hsa:59277; - UCSC; uc001tei.3; human. [Q9HB63-1] CTD; 59277; - DisGeNET; 59277; - EuPathDB; HostDB:ENSG00000074527.11; - GeneCards; NTN4; - HGNC; HGNC:13658; NTN4 HPA; HPA049832; - MIM; 610401; gene neXtProt; NX_Q9HB63; - OpenTargets; ENSG00000074527; - PharmGKB; PA31815; - eggNOG; KOG0994; Eukaryota eggNOG; ENOG410XPEG; LUCA GeneTree; ENSGT00780000121851; - HOVERGEN; HBG082019; - InParanoid; Q9HB63; - KO; K06845; - OMA; IVKGSCF; - OrthoDB; EOG091G0A35; - PhylomeDB; Q9HB63; - TreeFam; TF352481; - Reactome; R-HSA-3000171; Non-integrin membrane-ECM interactions Reactome; R-HSA-373752; Netrin-1 signaling SIGNOR; Q9HB63; - ChiTaRS; NTN4; human GenomeRNAi; 59277; - PRO; PR:Q9HB63; - Proteomes; UP000005640; Chromosome 12 Bgee; ENSG00000074527; - CleanEx; HS_NTN4; - ExpressionAtlas; Q9HB63; baseline and differential Genevisible; Q9HB63; HS GO; GO:0005604; C:basement membrane; IEA:UniProtKB-SubCell GO; GO:0005886; C:plasma membrane; TAS:Reactome GO; GO:0043237; F:laminin-1 binding; IEA:Ensembl GO; GO:0007411; P:axon guidance; TAS:Reactome GO; GO:0016322; P:neuron remodeling; IEA:Ensembl GO; GO:0060668; P:regulation of branching involved in salivary gland morphogenesis by extracellular matrix-epithelial cell signaling; IEA:Ensembl CDD; cd03578; NTR_netrin-4_like; 1 Gene3D; 2.60.120.1490; -; 1 InterPro; IPR002049; Laminin_EGF InterPro; IPR008211; Laminin_N InterPro; IPR038684; Laminin_N_sf InterPro; IPR035811; Netrin-4_NTR InterPro; IPR001134; Netrin_domain InterPro; IPR018933; Netrin_module_non-TIMP InterPro; IPR008993; TIMP-like_OB-fold Pfam; PF00053; Laminin_EGF; 3 Pfam; PF00055; Laminin_N; 1 Pfam; PF01759; NTR; 1 SMART; SM00643; C345C; 1 SMART; SM00180; EGF_Lam; 3 SMART; SM00136; LamNT; 1 SUPFAM; SSF50242; SSF50242; 1 PROSITE; PS00022; EGF_1; 2 PROSITE; PS01248; EGF_LAM_1; 2 PROSITE; PS50027; EGF_LAM_2; 3 PROSITE; PS51117; LAMININ_NTER; 1 PROSITE; PS50189; NTR; 1 1: Evidence at protein level; Alternative splicing; Basement membrane; Complete proteome; Disulfide bond; Extracellular matrix; Glycoprotein; Laminin EGF-like domain; Polymorphism; Reference proteome; Repeat; Secreted; Signal SIGNAL 1 18 CHAIN 19 628 Netrin-4 /FTId=PRO_0000042116 DOMAIN 30 261 Laminin N-terminal. {ECO:0000255|PROSITE- ProRule:PRU00466} DOMAIN 262 331 Laminin EGF-like 1. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 332 394 Laminin EGF-like 2. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 395 448 Laminin EGF-like 3. {ECO:0000255|PROSITE- ProRule:PRU00460} DOMAIN 506 627 NTR. {ECO:0000255|PROSITE- ProRule:PRU00295} CARBOHYD 56 56 N-linked (GlcNAc...) asparagine CARBOHYD 163 163 N-linked (GlcNAc...) asparagine CARBOHYD 353 353 N-linked (GlcNAc...) asparagine CARBOHYD 483 483 N-linked (GlcNAc...) asparagine DISULFID 262 271 DISULFID 264 293 DISULFID 295 304 DISULFID 307 329 DISULFID 332 341 DISULFID 334 359 DISULFID 362 371 DISULFID 374 392 DISULFID 395 413 DISULFID 397 420 DISULFID 422 431 DISULFID 434 446 DISULFID 506 576 DISULFID 520 627 VAR_SEQ 1 37 Missing (in isoform 3) {ECO:0000303|Ref.3} /FTId=VSP_015745 VAR_SEQ 504 526 Missing (in isoform 2) {ECO:0000303|Ref.4} /FTId=VSP_015746 VARIANT 205 205 Y -> H (in dbSNP:rs17288108) /FTId=VAR_023548 CONFLICT 68 68 T -> K (in Ref. 1; AAG30822) CONFLICT 161 161 A -> G (in Ref. 3; AAF69670) CONFLICT 222 222 T -> I (in Ref. 4; AAP92113) CONFLICT 331 331 T -> A (in Ref. 1 and 4). CONFLICT 462 462 C -> R (in Ref. 4; AAP92113) CONFLICT 472 472 Y -> C (in Ref. 1; AAG30822) CONFLICT 472 472 Y -> H (in Ref. 4; AAP92113) CONFLICT 545 545 N -> S (in Ref. 4; AAP92113) SEQUENCE 628 AA; 70071 MW; 275613B63A39B267 CRC64; MGSCARLLLL WGCTVVAAGL SGVAGVSSRC EKACNPRMGN LALGRKLWAD TTCGQNATEL YCFYSENTDL TCRQPKCDKC NAAYPHLAHL PSAMADSSFR FPRTWWQSAE DVHREKIQLD LEAEFYFTHL IVMFKSPRPA AMVLDRSQDF GKTWKPYKYF ATNCSATFGL EDDVVKKGAI CTSKYSSPFP CTGGEVIFKA LSPPYDTENP YSAKVQEQLK ITNLRVQLLK RQSCPCQRND LNEEPQHFTH YAIYDFIVKG SCFCNGHADQ CIPVHGFRPV KAPGTFHMVH GKCMCKHNTA GSHCQHCAPL YNDRPWEAAD GKTGAPNECR TCKCNGHADT CHFDVNVWEA SGNRSGGVCD DCQHNTEGQY CQRCKPGFYR DLRRPFSAPD ACKPCSCHPV GSAVLPANSV TFCDPSNGDC PCKPGVAGRR CDRCMVGYWG FGDYGCRPCD CAGSCDPITG DCISSHTDID WYHEVPDFRP VHNKSEPAWE WEDAQGFSAL LHSGKCECKE QTLGNAKAFC GMKYSYVLKI KILSAHDKGT HVEVNVKIKK VLKSTKLKIF RGKRTLYPES WTDRGCTCPI LNPGLEYLVA GHEDIRTGKL IVNMKSFVQH WKPSLGRKVM DILKRECK
Research Areas
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References

Koch M.,et al.J. Cell Biol. 151:221-234(2000).
Niranjan B.,et al.Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
Zhang C.,et al.Submitted (OCT-2003) to the EMBL/GenBank/DDBJ databases.
Li H.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.

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$ 295.00
Cat# AI13058
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