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FABP7 Antibody

Rabbit Monoclonal IgG

  • WB - FABP7 Antibody AJ1282a
    Western blot analysis on Fetal brain cell lysate using anti-FABP7 RabMAb (Cat. #AJ1282a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15540
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names EPR4000
Calculated MW 14889 Da
Gene ID 2173
Other Names Fatty acid-binding protein, brain, Brain lipid-binding protein, BLBP, Brain-type fatty acid-binding protein, B-FABP, Fatty acid-binding protein 7, Mammary-derived growth inhibitor related, FABP7, BLBP, FABPB, MRG
Target/Specificity A synthetic peptide corresponding to residues in human FABP7 was used as an immunogen.
Dilution WB~~1:1000~10000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFABP7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FABP7
Function B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity).
Cellular Location Cytoplasm.
Tissue Location Expressed in brain and other neural tissues.
Research Areas
Citations (0)

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FABP7 is a member of the large family of hydrophobic ligand-binding proteins (FABPs) (1). FABP proteins are involved in lipid metabolism, including uptake and intracellular trafficking of fatty acids and retinoids. In addition, they play a role in gene regulation, cell signaling, cell growth and differentiation. Several reports have suggested a possible role for the different FABP proteins in cancer biology, linking their levels with either increasing or decreasing the degree of malignancy. Nine FABPs (FABP1-FABP9) have been identified (2). FABP7 is a brain-specific protein that is required for the establishment of the radial glial fiber system in the developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (3). It is expressed at high levels in the developing central nervous system (4). FABP7 has also been found in melanocytic lesions and has shown to regulate proliferation and invasion in melanoma cells in vitro, suggesting that it may play a role in cell proliferation and invasion (2).


1. Anthony, T.E., et al., Genes Dev.19(9):1028-33, 2005 2. Slipicevic, A., et al. BMC Cancer 8:276, 2008 3. The UniProt Consortium. The Universal Protein Resource (UniProt). Nucleic Acids Res. 36:D190-D195 (2008) 4. Xu L.Z., et al., J Biol Chem. 271(40):24711-9, 1996

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Cat# AJ1282a
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