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LDH-A Antibody (muscle subunit)

Rabbit Monoclonal Antibody

  • WB - LDH-A Antibody (muscle subunit) AJ1437a
    A.Western blot analysis on (A) HeLa, (B) MCF-7, (C) A375 and (D) 293T cell lysates using anti-LDH-A (muscle subunit) RabMAb (Cat. #AJ1437a), dilution 1:1000.
  • IHC - LDH-A Antibody (muscle subunit) AJ1437a
    B. Immunohistochemical analysis of paraffin-embedded human muscles using anti-LDH-A (muscle subunit) RabMAb (Cat. #AJ1437a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00338
Reactivity Human, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EPR1564
Calculated MW 36689 Da
Gene ID 3939
Other Names L-lactate dehydrogenase A chain, LDH-A, Cell proliferation-inducing gene 19 protein, LDH muscle subunit, LDH-M, Renal carcinoma antigen NY-REN-59, LDHA
Target/Specificity A synthetic peptide corresponding to residues in human LDH-A (muscle subunit) was used as an immunogen.
Dilution WB~~1:1000~5000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLDH-A Antibody (muscle subunit) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Lactate dehydrogenase (LDH) is a ubiquitous enzyme commonly found in wide variety of organisms, including plants and microbes. LDH is involved in the interconversion of the pyruvate and NADH to lactate and NAD+. It is also called Hydroxybutyrate Dehydrogenase (HBD), due to the fact that it can catalyze the oxidation of hydroxybutyrate (1). Lactate dehydrogenase A (LDH-A, LDH muscle subunit, LDH-M) is involved in the final step of anaerobic glycoysis and catalyzes the conversion of L-lactate and NAD to pryruvate and NADH. While it is predominantly expressed in muscle tissue, it is hormonally regulated in rodents and overexpressed during mammary gland tumorigenesis (2). A mutation that cause deficiency in LDH-A has been implicated in exertional myoglobinuria (3).


1. Kopperschlager G et al. J Chromatogr B Biomed Appl. 684(1-2):25-49, 1996
2. Li X et al. Biochem Biophys Res Commun. 320(3):625-634, 2004
3. Kanno T et al. Clin Chim Acta. 173(1):89-98, 1998

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Cat# AJ1437a
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