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Musashi2 Antibody

Rabbit Monoclonal Antibody

  • WB - Musashi2 Antibody AJ1519a
    A. Western blot analysis on (A) Rat brain (B) Human brain (C) SW480 and (D) T47D cell lysates using anti-Musashi2 RabMAb (Cat. #AJ1519a).
  • IHC - Musashi2 Antibody AJ1519a
    B. Immunohistochemical analysis of paraffin-embedded human placenta using anti-Musashi2 RabMAb (Cat. #AJ1519a).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96DH6
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Monoclonal
Clone Names EP1305Y
Calculated MW 35197 Da
Gene ID 124540
Other Names RNA-binding protein Musashi homolog 2, Musashi-2, MSI2
Target/Specificity A synthetic peptide corresponding to N-terminus of human Musashi2 was used as an immunogen.
Dilution WB~~1:1000~2000
Format 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMusashi2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSI2
Function RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system (By similarity).
Cellular Location Cytoplasm. Note=Associated with polysomes.
Tissue Location Ubiquitous; detected at low levels.
Citations (0)

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Musashi2 (Msi2) is a member of Musashi family of evolutionarily conserved RNA-binding proteins. In mammals, Musashi1 and 2 shares similar primary structure, RNA binding specificity, and expression profile during CNS development. Highly co-expressed with Musashi1 in neural precursor cells, Musashi2 has been linked to proliferation and maintenance of stem cells in central nervous system. With two conserved tandem RNA recognition motifs, Musashi2 binds to target mRNAs and regulates RNA expression at translation level (1). Chromosomal aberrations involving Musashi2 might play a role in disease progression for chronic myeloid leukemia (2).


1. Sakakibara S, et al. The Journal of Neuroscience, 21(20):8091-8107, 2001.
2. Barbouti A, et al, Cancer Research 63:1202-1206, 2003.

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Cat# AJ1519a
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