|Dilution||IHC-P (20 µg/ml)|
|Other Names||Melatonin receptor type 1A, Mel-1A-R, Mel1a receptor, MTNR1A|
|Target/Specificity||Human MTNR1A. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||MTNR1A / Melatonin Receptor 1a Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High affinity receptor for melatonin. Likely to mediate the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in hypophyseal pars tuberalis and hypothalamic suprachiasmatic nuclei (SCN). Hippocampus|
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Provided below are standard protocols that you may find useful for product applications.
High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.
Reppert S.M.,et al.Neuron 13:1177-1185(1994).
Ebisawa T.,et al.Biochem. Biophys. Res. Commun. 262:832-837(1999).
Huang Y.-H.,et al.Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
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