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GLP1R / GLP-1 Receptor Antibody (Cytoplasmic Domain)

Rabbit Polyclonal Antibody

  • IHC - GLP1R / GLP-1 Receptor Antibody (Cytoplasmic Domain) ALS10299
    Anti-GLP1R antibody ALS10299 IHC of human pancreas.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P43220
Reactivity Human, Mouse, Rabbit, Hamster, Monkey, Pig, Horse, Dog
Host Rabbit
Clonality Polyclonal
Calculated MW 53kDa
Dilution IHC-P (6 µg/ml)
Additional Information
Gene ID 2740
Other Names Glucagon-like peptide 1 receptor, GLP-1 receptor, GLP-1-R, GLP-1R, GLP1R
Target/Specificity Human GLP1R. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PRPSAP2 (50%).
Reconstitution & Storage Long term: -70°C; Short term: +4°C
PrecautionsGLP1R / GLP-1 Receptor Antibody (Cytoplasmic Domain) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GLP1R
Function G-protein coupled receptor for glucagon-like peptide 1 (GLP-1) (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Ligand binding triggers activation of a signaling cascade that leads to the activation of adenylyl cyclase and increased intracellular cAMP levels (PubMed:8405712, PubMed:8216285, PubMed:7517895, PubMed:19861722, PubMed:26308095, PubMed:27196125, PubMed:28514449). Plays a role in regulating insulin secretion in response to GLP-1 (By similarity).
Cellular Location Cell membrane; Multi- pass membrane protein
Volume 50 µl
Research Areas
Citations (0)

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This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.


Thorens B.,et al.Diabetes 42:1678-1682(1993).
Dillon J.S.,et al.Endocrinology 133:1907-1910(1993).
Graziano M.P.,et al.Biochem. Biophys. Res. Commun. 196:141-146(1993).
van Eyll B.,et al.FEBS Lett. 348:7-13(1994).
Wei Y.,et al.FEBS Lett. 358:219-224(1995).

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$ 425.00
Cat# ALS10299
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