|Reactivity||Human, Rabbit, Monkey|
|Dilution||IHC-P (10 µg/ml)|
|Other Names||Glycogen phosphorylase, brain form, 188.8.131.52, PYGB|
|Target/Specificity||Human PYGB. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPBB / PYGB Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycogen phosphorylase that regulates glycogen mobilization (PubMed:27402852). Phosphorylase is an important allosteric enzyme in carbohydrate metabolism (PubMed:3346228). Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates (PubMed:3346228). However, all known phosphorylases share catalytic and structural properties (PubMed:3346228).|
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Provided below are standard protocols that you may find useful for product applications.
Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
Newgard C.B.,et al.J. Biol. Chem. 263:3850-3857(1988).
Gelinas R.P.,et al.Brain Res. Mol. Brain Res. 6:177-185(1989).
Deloukas P.,et al.Nature 414:865-871(2001).
Gevaert K.,et al.Nat. Biotechnol. 21:566-569(2003).
Bienvenut W.V.,et al.Submitted (JUL-2007) to UniProtKB.
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