|Reactivity||Human, Rabbit, Hamster, Monkey, Pig, Horse, Bovine, Dog|
|Dilution||IHC-P (6-14 µg/ml)|
|Other Names||G-protein coupled receptor 87, G-protein coupled receptor 95, GPR87, GPR95|
|Target/Specificity||Human GPR87. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except YSK4 (63%).|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||GPR87 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in placenta and prostate. Weaker expression in thymus. Not expressed in thalamus, hippocampus, pons or cerebellum. Overexpressed in squamous cell carcinoma of the lung.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
Urakawa I.,et al.Submitted (AUG-1999) to the EMBL/GenBank/DDBJ databases.
Lee D.K.,et al.Gene 275:83-91(2001).
Wittenberger T.,et al.J. Mol. Biol. 307:799-813(2001).
Kaighin V.A.,et al.Submitted (JUL-2008) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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