|Dilution||IHC-P (5-7.5 µg/ml)|
|Other Names||Bestrophin-3, Vitelliform macular dystrophy 2-like protein 3, BEST3, VMD2L3|
|Target/Specificity||Human BEST3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||VMD2L3 / BEST3 Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms calcium-sensitive chloride channels. Permeable to bicarbonate.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Present in skeletal muscle and weakly in brain, spinal cord, bone marrow and retina|
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Forms calcium-sensitive chloride channels. Permeable to bicarbonate.
Stoehr H.,et al.Eur. J. Hum. Genet. 10:281-284(2002).
Tsunenari T.,et al.J. Biol. Chem. 278:41114-41125(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Scherer S.E.,et al.Nature 440:346-351(2006).
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