|Dilution||IHC-P (2.5-5 µg/ml)|
|Other Names||Prominin-2, PROM-2, Prominin-like protein 2, hPROML2, PROM2, PROML2|
|Target/Specificity||Human PROM2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.|
|Reconstitution & Storage||Long term: -70°C; Short term: +4°C|
|Precautions||Prominin 2 / PROM2 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Apical cell membrane; Multi- pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Cell projection, cilium membrane; Multi-pass membrane protein Note=Colocalizes with PROM1. Associates with membrane in a cholesterol-dependent manner. Localizes to the apical and basolateral membranes of epithelial cells (By similarity)|
|Tissue Location||Present in saliva within small membrane particles (at protein level). Expressed in kidney, prostate, trachea, esophagus, salivary gland, thyroid gland, mammary gland adrenal gland, placenta, stomach, spinal cord and liver. In submucosal tumor, expressed in spindle-shaped or stellate stromal cells. Expressed in prostate cancer cell lines|
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Provided below are standard protocols that you may find useful for product applications.
Fargeas C.A.,et al.J. Biol. Chem. 278:8586-8596(2003).
Clark H.F.,et al.Genome Res. 13:2265-2270(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 434:724-731(2005).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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