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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BAIAP3 Antibody (aa1171-1187)   

BAIAP3 Antibody (aa1171-1187)

Rabbit Polyclonal Antibody

  • IHC - BAIAP3 Antibody (aa1171-1187) ALS11267
    Anti-BAIAP3 antibody IHC of human brain, cortex.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O94812
Reactivity Human
Host Rabbit
Clonality Polyclonal
Calculated MW 132kDa
Dilution ELISA (1:1000), IHC-P (10 µg/ml),
Additional Information
Gene ID 8938
Other Names BAI1-associated protein 3, BAP3, BAIAP3, KIAA0734
Target/Specificity Amino acids 1171 to 1187 of human BAIAP3
Reconstitution & Storage Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
PrecautionsBAIAP3 Antibody (aa1171-1187) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BAIAP3 {ECO:0000303|PubMed:28626000, ECO:0000312|HGNC:HGNC:948}
Function Functions in endosome to Golgi retrograde transport. In response to calcium influx, may interact with SNARE fusion receptors and membrane phospholipids to mediate endosome fusion with the trans-Golgi network. By promoting the recycling of secretory vesicle transmembrane proteins, it indirectly controls dense-core secretory vesicle biogenesis, maturation and their ability to mediate the constitutive and regulated secretion of neurotransmitters and hormones. May regulate behavior and food intake by controlling calcium-stimulated exocytosis of neurotransmitters including NPY and serotonin and hormones like insulin (PubMed:28626000). Proposed to play a role in hypothalamic neuronal firing by modulating gamma-aminobutyric acid (GABA)ergic inhibitory neurotransmission (By similarity).
Cellular Location Cytoplasm, cytosol. Recycling endosome membrane; Peripheral membrane protein. Late endosome membrane; Peripheral membrane protein. Golgi apparatus, trans-Golgi network membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Note=Rapidly recruited to the plasma membrane and to Golgi structures in response to increased intracellular calcium concentration
Tissue Location Predominantly expressed in brain (PubMed:9790924). Also expressed in nonneural tissues such as breast and testes epithelium (PubMed:12498718)
Research Areas
Citations (0)

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Shiratsuchi T.,et al.Biochem. Biophys. Res. Commun. 251:158-165(1998).
Nagase T.,et al.DNA Res. 5:277-286(1998).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 425.00
Cat# ALS11267
Availability: 5 days
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