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Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P |
|---|---|
| Primary Accession | P30304 |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Calculated MW | 59kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 993 |
|---|---|
| Other Names | M-phase inducer phosphatase 1, 3.1.3.48, Dual specificity phosphatase Cdc25A, CDC25A |
| Target/Specificity | Amino acids surrounding Ser 75 of human CDC25A |
| Reconstitution & Storage | Long term: -20°C; Short term: -20°C |
| Precautions | CDC25A Antibody (Ser75) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CDC25A |
|---|---|
| Function | Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDK1 and stimulates its kinase activity. Also dephosphorylates CDK2 in complex with cyclin E, in vitro.
References
Galaktionov K.I.,et al.Cell 67:1181-1194(1991).
Varmeh-Ziaie S.,et al.Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Wegener S.,et al.Eur. J. Cell Biol. 79:810-815(2000).
Falck J.,et al.Nature 410:842-847(2001).
Donzelli M.,et al.EMBO J. 21:4875-4884(2002).
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