|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (0.5-1 µg/ml),|
|Other Names||Neurosecretory protein VGF, Neuroendocrine regulatory peptide-1, NERP-1, Neuroendocrine regulatory peptide-2, NERP-2, Antimicrobial peptide VGF[554-577], VGF|
|Target/Specificity||The immunogen is after amino acid 577 of O15240, so the antibody should only cross-react with full-length VGF and none of the processed peptides.|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||VGF Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system.|
|Cellular Location||Secreted. Cytoplasmic vesicle, secretory vesicle. Note=Stored in secretory vesicles and then secreted, NERP peptides colocalize with vasopressin in the storage granules of hypothalamus|
|Tissue Location||Central and peripheral nervous systems, synthesized exclusively in neuronal and neuroendocrine cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
May be involved in the regulation of cell-cell interactions or in synatogenesis during the maturation of the nervous system. Antimicrobial peptide VGF[554-577]: Has bactericidal activity against M. luteus, and antifungal activity against P. Pastoris.
Canu N.,et al.Genomics 45:443-446(1997).
Hillier L.W.,et al.Nature 424:157-164(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Sasaki K.,et al.Mol. Cell. Proteomics 12:700-709(2013).
Toshinai K.,et al.Cell. Mol. Life Sci. 66:1939-1945(2009).
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