|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (10-20 µg/ml), WB (1 µg/ml),|
|Other Names||43 kDa receptor-associated protein of the synapse, RAPsyn, 43 kDa postsynaptic protein, Acetylcholine receptor-associated 43 kDa protein, RING finger protein 205, RAPSN, RNF205|
|Target/Specificity||Synthetic peptide corresponding to C-terminal residues of human RAPSN(43 kD receptor-associated protein of the synapse).|
|Reconstitution & Storage||+4°C or -20°C, Avoid repeated freezing and thawing.|
|Precautions||RAPSN Antibody (aa399-412) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.|
|Cellular Location||Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse, postsynaptic cell membrane; Peripheral membrane protein; Cytoplasmic side Cytoplasm, cytoskeleton. Note=Cytoplasmic surface of postsynaptic membranes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Postsynaptic protein required for clustering of nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction. It may link the receptor to the underlying postsynaptic cytoskeleton, possibly by direct association with actin or spectrin.
Buckel A.,et al.Genomics 35:613-616(1996).
Ohno K.,et al.Am. J. Hum. Genet. 70:875-885(2002).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Nam S.,et al.J. Biol. Chem. 284:8195-8206(2009).
Dunne V.,et al.J. Hum. Genet. 48:204-207(2003).
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