|Application ||WB, IHC-P, E|
|Reactivity||Human, Mouse, Rat, Monkey, Bovine|
|Dilution||ELISA (1:64000), IHC-P (3.75 µg/ml), WB (1-3 µg/ml)|
|Other Names||Glutamyl aminopeptidase, EAP, 188.8.131.52, Aminopeptidase A, AP-A, Differentiation antigen gp160, CD249, ENPEP|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||ENPEP / Aminopeptidase A Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates central hypertension through its calcium- modulated preference to cleave N-terminal acidic residues from peptides such as angiotensin II.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in choriocarcinoma cancer cell lines (at protein level) (PubMed:10692253). Expressed by epithelial cells of the proximal tubule cells and the glomerulus of the nephron. Also found in a variety of other tissues|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Appears to have a role in the catabolic pathway of the renin-angiotensin system. Probably plays a role in regulating growth and differentiation of early B-lineage cells.
Nanus D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:7069-7073(1993).
Li L.,et al.Genomics 17:657-664(1993).
Hillier L.W.,et al.Nature 434:724-731(2005).
Liu T.,et al.J. Proteome Res. 4:2070-2080(2005).
Chen R.,et al.J. Proteome Res. 8:651-661(2009).
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