|Application ||IHC-P, E|
|Dilution||ELISA (1:8000), IHC-P (2 µg/ml),|
|Other Names||Appetite-regulating hormone, Growth hormone secretagogue, Growth hormone-releasing peptide, Motilin-related peptide, Protein M46, Ghrelin-27, Ghrelin-28, Ghrelin, Obestatin, GHRL, MTLRP|
|Target/Specificity||Human GHRL / Ghrelin. This antibody is expected to recognise all reported isoforms.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||GHRL / Ghrelin Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.|
|Tissue Location||Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy|
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Provided below are standard protocols that you may find useful for product applications.
Ghrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation.
Kojima M.,et al.Nature 402:656-660(1999).
Tomasetto C.,et al.Gastroenterology 119:395-405(2000).
Wajnrajch M.P.,et al.J. Endocr. Genet. 1:231-233(2000).
Hosoda H.,et al.J. Biol. Chem. 278:64-70(2003).
Seim I.,et al.BMC Genomics 8:298-298(2007).
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