|Application ||WB, IHC-P, E|
|Dilution||ELISA (1:128000), IHC-P (4 µg/ml), WB (0.1-0.3 µg/ml)|
|Other Names||Aromatase, 188.8.131.52, CYPXIX, Cytochrome P-450AROM, Cytochrome P450 19A1, Estrogen synthase, CYP19A1, ARO1, CYAR, CYP19|
|Target/Specificity||Human CYP19A1 / Aromatase. This antibody is expected to recognise both reported isoforms (NP_000094.2 and NP_112503.1), which are identical|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||CYP19 / Aromatase Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ARO1, CYAR, CYP19|
|Function||Catalyzes the formation of aromatic C18 estrogens from C19 androgens.|
|Cellular Location||Membrane; Peripheral membrane protein.|
|Tissue Location||Widely expressed, including in adult and fetal brain, placenta, skin fibroblasts, adipose tissue and gonads|
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Provided below are standard protocols that you may find useful for product applications.
Catalyzes the formation of aromatic C18 estrogens from C19 androgens.
Harada N.,et al.Biochem. Biophys. Res. Commun. 156:725-732(1988).
Chen S.,et al.DNA 7:27-38(1988).
Corbin C.J.,et al.Proc. Natl. Acad. Sci. U.S.A. 85:8948-8952(1988).
Toda K.,et al.FEBS Lett. 247:371-376(1989).
Means G.D.,et al.J. Biol. Chem. 264:19385-19391(1989).
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