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Goat Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, E |
|---|---|
| Primary Accession | P15428 |
| Reactivity | Human, Monkey |
| Host | Goat |
| Clonality | Polyclonal |
| Calculated MW | 29kDa |
| Dilution | ELISA (1:128000), IHC-P (2.5 µg/ml), WB (0.1-1 µg/ml) |
| Gene ID | 3248 |
|---|---|
| Other Names | 15-hydroxyprostaglandin dehydrogenase [NAD(+)], 15-PGDH, 1.1.1.141, Prostaglandin dehydrogenase 1, HPGD, PGDH1 |
| Target/Specificity | Human HPGD / 15-PGDH. |
| Reconstitution & Storage | Store at -20°C. Minimize freezing and thawing. |
| Precautions | 15-PGDH / HPGD Antibody (C-Terminus) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HPGD |
|---|---|
| Synonyms | PGDH1, SDR36C1 |
| Function | Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells. |
| Cellular Location | Cytoplasm. |
| Tissue Location | Detected in colon epithelium (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Prostaglandin inactivation. Contributes to the regulation of events that are under the control of prostaglandin levels. Catalyzes the NAD-dependent dehydrogenation of lipoxin A4 to form 15-oxo-lipoxin A4. Inhibits in vivo proliferation of colon cancer cells.
References
Krook M.,et al.Biochemistry 29:738-743(1990).
Ensor C.M.,et al.J. Biol. Chem. 265:14888-14891(1990).
Pichaud F.,et al.Gene 162:319-322(1995).
Delage-Mourroux R.,et al.Gene 188:143-148(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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