|Application ||WB, IHC-P, IF|
|Reactivity||Human, Mouse, Rat|
|Dilution||IHC-P (5 µg/ml), WB (2 µg/ml),|
|Other Names||Metalloreductase STEAP1, 1.16.1.-, Six-transmembrane epithelial antigen of prostate 1, STEAP1, PRSS24, STEAP|
|Target/Specificity||a 16 amino acid peptide from near the center of human STEAP1|
|Reconstitution & Storage||Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles. Store undiluted.|
|Precautions||STEAP1 / STEAP Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).|
|Cellular Location||Endosome membrane; Multi-pass membrane protein|
|Tissue Location||Ubiquitously expressed. Highly expressed in prostate tumors.|
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Provided below are standard protocols that you may find useful for product applications.
Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor (By similarity).
Hubert R.S.,et al.Proc. Natl. Acad. Sci. U.S.A. 96:14523-14528(1999).
Hillier L.W.,et al.Nature 424:157-164(2003).
Scherer S.W.,et al.Science 300:767-772(2003).
Ohgami R.S.,et al.Blood 108:1388-1394(2006).
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