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Mouse Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IHC-P, IF, E, IP, Flo |
|---|---|
| Primary Accession | P01106 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 9E10 |
| Calculated MW | 49kDa |
| Dilution | IHC-P (10 µg/ml) |
| Gene ID | 4609 |
|---|---|
| Other Names | Myc proto-oncogene protein, Class E basic helix-loop-helix protein 39, bHLHe39, Proto-oncogene c-Myc, Transcription factor p64, MYC, BHLHE39 |
| Target/Specificity | Amino acids 408-439, C-terminal region of human c-myc. |
| Reconstitution & Storage | +4°C. Store undiluted. |
| Precautions | MYC / c-Myc Antibody (aa408-439, clone 9E10) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | MYC |
|---|---|
| Synonyms | BHLHE39 |
| Function | Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis (PubMed:24940000). |
| Cellular Location | Nucleus, nucleoplasm. Nucleus, nucleolus |
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Provided below are standard protocols that you may find useful for product applications.
Background
Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes.
References
Battey J.,et al.Cell 34:779-787(1983).
Bernard O.,et al.EMBO J. 2:2375-2383(1983).
Colby W.W.,et al.Nature 301:722-725(1983).
Watt R.,et al.Nature 303:725-728(1983).
Rabbitts T.H.,et al.Nature 306:760-765(1983).
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