|Dilution||IHC-P (3.75 µg/ml)|
|Other Names||Sodium/glucose cotransporter 1, Na(+)/glucose cotransporter 1, High affinity sodium-glucose cotransporter, Solute carrier family 5 member 1, SLC5A1, NAGT, SGLT1|
|Target/Specificity||Human SLC5A1 / SGLT1.|
|Reconstitution & Storage||Store at -20°C. Minimize freezing and thawing.|
|Precautions||SLC5A1 / SGLT1 Antibody (Internal) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed mainly in intestine and kidney.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Actively transports glucose into cells by Na(+) cotransport with a Na(+) to glucose coupling ratio of 2:1. Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
Hediger M.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5748-5752(1989).
Turk E.,et al.J. Biol. Chem. 269:15204-15209(1994).
Collins J.E.,et al.Genome Biol. 5:R84.1-R84.11(2004).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Dunham I.,et al.Nature 402:489-495(1999).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.